Baker R A, Tatum J H, Nemec S
U.S. Citrus and Subtropical Products Laboratory, Winter Haven, FL 33883-1909.
Mycopathologia. 1990 Jul;111(1):9-15. doi: 10.1007/BF02277294.
Twenty-two naphthoquinone compounds isolated or derived synthetically from culture extracts of Fusarium solani and F. oxysporum were examined for antimicrobial activity. Fifteen exhibited antibiotic activity against Staphylococcus aureus, and 12 were active against Streptococcus pyogenes, but none were active at the highest rate of 128 micrograms/ml against Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Proteus vulgaris, Serratia marcescens, or Pseudomonas aeruginosa. Of 8 plant pathogenic bacteria tested against 11 naphthoquinones, Corynebacterium poinsettiae was inhibited by 6 compounds, and Pseudomonas viridiflava was weakly inhibited by one. Only one of a group of 6 fluorescent soil pseudomonads was inhibited by one naphthoquinone. Antifungal activity of 10 compounds against 8 fungal plant pathogens was limited to inhibition of Phytophthora parasitica by one naphthopyran.
对从茄腐镰刀菌和尖孢镰刀菌培养提取物中分离或合成得到的22种萘醌化合物进行了抗菌活性检测。其中15种对金黄色葡萄球菌具有抗菌活性，12种对化脓性链球菌有活性，但在最高浓度128微克/毫升时，对大肠杆菌、肺炎克雷伯菌、伤寒沙门氏菌、普通变形杆菌、粘质沙雷氏菌或铜绿假单胞菌均无活性。在针对11种萘醌测试的8种植物病原菌中，6种化合物抑制了一品红棒杆菌，1种化合物对绿黄假单胞菌有微弱抑制作用。6种荧光土壤假单胞菌中只有1种被1种萘醌抑制。10种化合物对8种植物病原真菌的抗真菌活性仅限于1种萘并吡喃对寄生疫霉的抑制作用。
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