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系统生物学方法中的组学技术在中医药研究中的应用:现状与展望。

Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

机构信息

Institute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.

出版信息

J Ethnopharmacol. 2012 Apr 10;140(3):535-44. doi: 10.1016/j.jep.2012.01.055. Epub 2012 Feb 8.

DOI:10.1016/j.jep.2012.01.055
PMID:22342380
Abstract

Omic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for the application of omics in TCM research are also proposed.

摘要

组学技术已成为系统生物学发展的关键工具。由于传统中医(TCM)实践所基于的整体方法和西医向个体化医学发展的新趋势需要深入了解作用机制和活性化合物,因此组学技术对于理解和解释 TCM 的发展至关重要,特别是考虑到 TCM 在西方国家的扩展。在这篇简短的综述中,回顾了组学在 TCM 研究中的应用,这使得人们可以对这些方法在 TCM 现代化和标准化方面的未来前景进行一些推测。还提出了组学在 TCM 研究中应用的良好实践指南。

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