Netherlands Institute for Neuroscience, Royal Netherlands Academy for Arts and Sciences, Amsterdam, The Netherlands.
PLoS One. 2012;7(2):e31764. doi: 10.1371/journal.pone.0031764. Epub 2012 Feb 10.
This study optically determines whether the amount of light scatter due to laser-induced damage to the intraocular lens (IOL) is significant in relation to normal straylight values in the human eye. Two IOLs with laser-induced damage were extracted from two donor eyes. Each IOL had 15 pits and/or cracks. The surface area of each pit was measured using a microscope. For 6 pits per intraocular lens the point spread function (PSF) in terms of straylight was measured and the total straylight for all 15 pits was estimated. The damage in the IOLs was scored as mild/moderate. The total damaged surface areas, for a 3.5 mm pupil, in the two IOLs were 0.13% (0.0127 mm(2)) and 0.66% (0.064 mm(2)), respectively. The angular dependence of the straylight caused by the damage was similar to that of the normal PSF. The total average contribution to straylight was log(s) = -0.82 and -0.42, much less than the straylight value of the normal eye.The straylight due to normal levels of laser induced damage of the IOL is much lower than normal straylight values found clinically for the normal eye and may therefore be considered not significant.
这项研究通过光学方法确定了激光对内眼人工晶状体（IOL）造成的光散射量与正常人眼的正常杂散光值相比是否显著。从两只供体眼中提取了两个有激光损伤的 IOL。每个 IOL 有 15 个凹坑和/或裂缝。使用显微镜测量每个凹坑的表面积。对于每个 IOL 的 6 个凹坑，测量了以杂散光表示的点扩散函数（PSF），并估计了所有 15 个凹坑的总杂散光。IOL 中的损伤评分为轻度/中度。在两个 IOL 中，对于 3.5mm 瞳孔，两个 IOL 的总损伤表面积分别为 0.13%（0.0127mm²）和 0.66%（0.064mm²）。损伤引起的杂散光的角度依赖性与正常 PSF 的角度依赖性相似。总平均杂散光贡献为 log(s)=-0.82 和 -0.42，远低于临床正常眼的杂散光值。IOL 正常水平的激光诱导损伤引起的杂散光远低于临床正常眼发现的正常杂散光值，因此可以认为不显著。
