Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.
J Eur Acad Dermatol Venereol. 2012 Oct;26(10):1203-11. doi: 10.1111/j.1468-3083.2012.04475.x. Epub 2012 Feb 20.
Diabetes mellitus is the most common endocrine disorder with continuously increasing prevalence. Blood vessels, nerves, eyes, kidneys and skin are affected, which causes both an enormous financial burden and a reduced quality of life of the affected patients. Long-standing diabetes may impair skin homeostasis resulting in skin manifestations in at least one third of all diabetics. The skin involvement may be the first presenting sign of diabetes, thus the respective skin signs should lead to diabetes focused diagnostic. Besides, the skin signs may be considered as a marker for the course of the disease or for the success of therapeutic interventions.
糖尿病是最常见的内分泌紊乱疾病，其患病率持续上升。血管、神经、眼睛、肾脏和皮肤都会受到影响，这不仅给患者带来了巨大的经济负担，还降低了他们的生活质量。长期的糖尿病可能会损害皮肤的内稳态，导致至少三分之一的糖尿病患者出现皮肤表现。皮肤受累可能是糖尿病的首发表现，因此相应的皮肤表现应该促使我们对糖尿病进行有针对性的诊断。此外，皮肤表现还可以作为疾病进程或治疗干预效果的标志物。
