用于研究抗病毒药物预防潜伏性单纯疱疹病毒再激活效果的体外系统。
In vitro system for studying the efficacy of antiviral agents in preventing the reactivation of latent herpes simplex virus.
作者信息
Wohlenberg C, Openshaw H, Notkins A L
出版信息
Antimicrob Agents Chemother. 1979 Apr;15(4):625-7. doi: 10.1128/AAC.15.4.625.
Abstract
Antiviral antibody and interferon did not prevent in vitro reactivation of herpes simplex virus in latently infected sensory ganglia. Phosphonoacetic acid and 9-beta-d-arabinofuranosyladenine blocked reactivation, but this treatment did not eradicate the latent infection.
摘要
抗病毒抗体和干扰素不能阻止潜伏感染的感觉神经节中单纯疱疹病毒的体外再激活。膦甲酸和9-β-D-阿拉伯呋喃糖基腺嘌呤可阻断再激活，但这种治疗并不能根除潜伏感染。
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本文引用的文献
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Activation of latent herpes simplex by trigeminal sensory-root section.通过三叉神经感觉根切断术激活潜伏的单纯疱疹病毒。
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Latent ganglionic infection with herpes simplex virus types 1 and 2: viral reactivation in vivo after neurectomy.1型和2型单纯疱疹病毒的潜伏性神经节感染：神经切除术后体内的病毒再激活
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Latent herpes simplex virus in spinal ganglia of mice.小鼠脊髓神经节中的潜伏性单纯疱疹病毒
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Heterogeneity in the properties of 7 S and 19S rabbit-neutralizing antibodies to herpes simplex virus.兔抗单纯疱疹病毒7S和19S中和抗体特性的异质性
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Rational design of arabinosyl nucleosides as antitumor and antiviral agents.阿拉伯糖基核苷作为抗肿瘤和抗病毒药物的合理设计。
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Pharmacology and chemistry of some inhibitors of herpes replication.某些疱疹复制抑制剂的药理学与化学
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Latent characteristics of selected herpesviruses.所选疱疹病毒的潜在特征。
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