Capricious Cre: the devil is in the details.
作者信息
Morrison Christopher D, Münzberg Heike
机构信息
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA.
出版信息
Endocrinology. 2012 Mar;153(3):1005-7. doi: 10.1210/en.2011-2169.
Abstract
摘要
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本文引用的文献
1
Defining POMC neurons using transgenic reagents: impact of transient Pomc expression in diverse immature neuronal populations.使用转基因试剂定义 POMC 神经元：瞬时 Pomc 表达对不同未成熟神经元群体的影响。
Endocrinology. 2012 Mar;153(3):1219-31. doi: 10.1210/en.2011-1665. Epub 2011 Dec 13.
2
Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality.脂肪蛋白 2-cre 介导的 von Hippel-Lindau 基因敲除导致缺氧诱导因子 1 激活，引起胚胎致死。
Clin Exp Pharmacol Physiol. 2012 Feb;39(2):145-50. doi: 10.1111/j.1440-1681.2011.05656.x.
3
Leptin does not directly affect CNS serotonin neurons to influence appetite.瘦素不会直接影响中枢神经系统的 5-羟色胺神经元来影响食欲。
Cell Metab. 2011 May 4;13(5):584-91. doi: 10.1016/j.cmet.2011.03.016.
4
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.AgRP 神经元的快速、可逆激活驱动小鼠的摄食行为。
J Clin Invest. 2011 Apr;121(4):1424-8. doi: 10.1172/JCI46229.
5
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training.AGRP 神经元足以快速协调进食行为，而无需进行训练。
Nat Neurosci. 2011 Mar;14(3):351-5. doi: 10.1038/nn.2739. Epub 2010 Jan 5.
6
Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits.表达 Pomc 的祖细胞在下丘脑摄食回路中产生拮抗的神经元群体。
Nat Med. 2010 Apr;16(4):403-5. doi: 10.1038/nm.2126. Epub 2010 Mar 28.
7
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion.瘦素受体调节的神经元在控制新陈代谢和摄食方面的集体和个体功能。
Endocrinology. 2008 Apr;149(4):1773-85. doi: 10.1210/en.2007-1132. Epub 2007 Dec 27.
8
Early postnatal astroglial cells produce multilineage precursors and neural stem cells in vivo.出生后早期的星形胶质细胞在体内产生多谱系前体细胞和神经干细胞。
J Neurosci. 2006 Aug 16;26(33):8609-21. doi: 10.1523/JNEUROSCI.2532-06.2006.
9
Nestin-Cre transgenic mouse line Nes-Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite-derived tissues.巢蛋白-Cre转基因小鼠品系Nes-Cre1在神经系统、肾脏和体节衍生组织中介导高效的Cre/loxP介导的重组。
Genesis. 2006 Aug;44(8):355-60. doi: 10.1002/dvg.20226.
10
GFAP-positive progenitor cells produce neurons and oligodendrocytes throughout the CNS.胶质纤维酸性蛋白阳性祖细胞在整个中枢神经系统中产生神经元和少突胶质细胞。
Mol Cell Neurosci. 2006 Apr;31(4):676-84. doi: 10.1016/j.mcn.2005.12.006. Epub 2006 Feb 3.
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