Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Ann Oncol. 2012 Apr;23(4):1044-52. doi: 10.1093/annonc/mds024. Epub 2012 Feb 28.
Estimating current cancer mortality figures is important for defining priorities for prevention and treatment.
Using logarithmic Poisson count data joinpoint models on mortality and population data from the World Health Organization database, we estimated numbers of deaths and age-standardized rates in 2012 from all cancers and selected cancer sites for the whole European Union (EU) and its six more populated countries.
Cancer deaths in the EU in 2012 are estimated to be 1,283,101 (717,398 men and 565,703 women) corresponding to standardized overall cancer death rates of 139/100,000 men and 85/100,000 women. The fall from 2007 was 10% in men and 7% in women. In men, declines are predicted for stomach (-20%), leukemias (-11%), lung and prostate (-10%) and colorectal (-7%) cancers, and for stomach (-23%), leukemias (-12%), uterus and colorectum (-11%) and breast (-9%) in women. Almost stable rates are expected for pancreatic cancer (+2-3%) and increases for female lung cancer (+7%). Younger women show the greatest falls in breast cancer mortality rates in the EU (-17%), and declines are expected in all individual countries, except Poland.
Apart for lung cancer in women and pancreatic cancer, continuing falls are expected in mortality from major cancers in the EU.
评估当前癌症死亡率对于确定预防和治疗重点非常重要。
我们使用对数泊松计数数据连接点模型,根据世界卫生组织数据库中的死亡率和人口数据,估计了 2012 年整个欧盟及其六个人口较多的国家所有癌症和选定癌症部位的死亡人数和年龄标准化率。
欧盟 2012 年癌症死亡人数估计为 1,283,101 人(717,398 名男性和 565,703 名女性),标准化总体癌症死亡率为男性 139/100,000,女性 85/100,000。与 2007 年相比,男性下降了 10%,女性下降了 7%。在男性中,预计胃癌(-20%)、白血病(-11%)、肺癌和前列腺癌(-10%)和结直肠癌(-7%)以及胃癌(-23%)、白血病(-12%)、子宫和结直肠癌(-11%)和乳腺癌(-9%)的发病率将会下降。胰腺癌(+2-3%)和女性肺癌(+7%)的发病率预计将保持稳定。在欧盟,年轻女性的乳腺癌死亡率下降幅度最大(-17%),除波兰外,所有国家的这一比例预计都会下降。
除了女性肺癌和胰腺癌外,欧盟主要癌症的死亡率预计将继续下降。