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大量社交饮酒对执行功能的影响:对现有文献及新实证研究结果的系统评价与荟萃分析

The effects of heavy social drinking on executive function: a systematic review and meta-analytic study of existing literature and new empirical findings.

作者信息

Montgomery Catharine, Fisk John E, Murphy Philip N, Ryland Ida, Hilton Joanne

机构信息

Department of Psychology, School of Natural Sciences & Psychology, Liverpool, UK.

出版信息

Hum Psychopharmacol. 2012 Mar;27(2):187-99. doi: 10.1002/hup.1268.

Abstract

BACKGROUND

Previous investigations of executive function in alcohol dependent and in social drinkers have not always produced consistent results and have not utilised key indicators of recent theoretical models of Executive Function (EF). The present paper reports the results of two studies that seek to address these limitations.

METHOD

Study 1 took the form of a systematic review and meta-analysis of studies examining EF in social drinkers. In Study 2, 41 participants completed an alcohol use inventory and were assigned to either light or heavy alcohol use via median split of average weekly dose. Participants completed measures of the fractionated executive processes of updating, shifting, inhibition and access to semantic memory.

RESULTS

Study 1 only identified seven studies of EF in social drinkers, and the mean effect size was non-significant. In study 2, the heavy alcohol use group performed worse on all measures of executive functioning except memory updating.

CONCLUSIONS

To our knowledge, this is the first systematic investigation of executive functioning in social drinkers. Given that the participants were non-treatment seeking social drinking students, the EF deficit in the heavy user group is particularly worrying and could increase the likelihood of developing an alcohol use disorder.

摘要

背景

先前对酒精依赖者和社交饮酒者执行功能的调查结果并不总是一致,且未采用执行功能(EF)近期理论模型的关键指标。本文报告了两项旨在解决这些局限性的研究结果。

方法

研究1采用对考察社交饮酒者执行功能的研究进行系统评价和荟萃分析的形式。在研究2中,41名参与者完成了一份酒精使用量表,并通过平均每周饮酒量的中位数分割被分为轻度或重度饮酒组。参与者完成了关于更新、转换、抑制和语义记忆提取等细分执行过程的测量。

结果

研究1仅识别出七项关于社交饮酒者执行功能的研究,平均效应量不显著。在研究2中,重度饮酒组在除记忆更新外的所有执行功能测量中表现更差。

结论

据我们所知,这是对社交饮酒者执行功能的首次系统调查。鉴于参与者是未寻求治疗的社交饮酒学生,重度饮酒组的执行功能缺陷尤其令人担忧,可能会增加发展为酒精使用障碍的可能性。

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