Bajbouj M
II. Medizinische Klinik, Klinikum rechts der Isar, TU München, Ismaningerstr. 22, 81575, München, Deutschland.
HNO. 2012 Mar;60(3):193-9. doi: 10.1007/s00106-011-2430-9.
Gastroesophageal reflux disease (GERD) is a frequent chronic disorder occurring in two forms: on the one hand, typical symptoms such as heartburn and acid regurgitation are seen, while on the other hand atypical (extraesophageal) symptoms such as chronic cough, hoarseness, recurrent sinusitis, globus sensations in the throat, a burning feeling on the tongue, dental erosions and the constant need to clear the throat can be associated with gastroesophageal reflux. The standard therapeutic medical procedure comprises the administration of acid-suppressive agents, proton pump inhibitors (PPI). However, this therapy has proved to be ineffective in a number of patients, especially in atypical GERD. Only after reliable identification of the GERD patient by using valid diagnostic tools medical or interventional therapeutic options can be applied individually. In the absence of atypical GERD symptoms, the diagnosis of GERD becomes very unlikely and other causes of the symptoms need to be taken into consideration.
胃食管反流病（GERD）是一种常见的慢性疾病，有两种表现形式：一方面，会出现烧心和反酸等典型症状；另一方面，慢性咳嗽、声音嘶哑、复发性鼻窦炎、咽喉部异物感、舌头发热感、牙齿侵蚀以及持续清嗓等非典型（食管外）症状可能与胃食管反流有关。标准的治疗医疗程序包括使用抑酸剂，即质子泵抑制剂（PPI）。然而，这种疗法在许多患者中已被证明无效，尤其是在非典型GERD患者中。只有在通过有效的诊断工具可靠地识别出GERD患者后，才能单独应用医学或介入性治疗方案。在没有非典型GERD症状的情况下，GERD的诊断极不可能成立，需要考虑症状的其他原因。
