McLeod S D, West S K, Quigley H A, Fozard J L
Dana Center for Preventive Ophthalmology, Wilmer Institute, Johns Hopkins Hospital, Baltimore, MD 21205.
Invest Ophthalmol Vis Sci. 1990 Nov;31(11):2361-6.
The relationship between intraocular and systemic blood pressures was investigated in a prospective study of 572 middle-aged men. There was no consistent relationship between intraocular pressure at first visit and age. Subjects with an intraocular pressure greater than 20 mm Hg had a significantly higher systolic blood pressure than controls matched for age. An autoregressive model was used to examine the relationship between change in intraocular pressure and initial intraocular pressure, age, and blood pressure. When the authors compared data obtained 1 or 2 years apart, a change in intraocular pressure was positively correlated with a change in systolic blood pressure. Thus, the results of this study indicate that changes in intraocular pressure over time are associated with changes in systolic blood pressure and that intraocular pressure does not necessarily increase with age.
在一项针对572名中年男性的前瞻性研究中，研究了眼内压与全身血压之间的关系。首次就诊时的眼内压与年龄之间没有一致的关系。眼内压高于20 mmHg的受试者的收缩压显著高于年龄匹配的对照组。使用自回归模型来检验眼内压变化与初始眼内压、年龄和血压之间的关系。当作者比较相隔1年或2年获得的数据时，眼内压的变化与收缩压的变化呈正相关。因此，本研究结果表明，眼内压随时间的变化与收缩压的变化相关，且眼内压不一定随年龄增长而升高。
