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乳制品摄入与心脏代谢健康:为期 12 个月的交叉试验结果。

Dairy consumption and cardiometabolic health: outcomes of a 12-month crossover trial.

机构信息

Nutritional Physiology Research Centre, University of South Australia, GPO Box 2471, Adelaide, South Australia 5001, Australia.

出版信息

Nutr Metab (Lond). 2012 Mar 20;9:19. doi: 10.1186/1743-7075-9-19.

Abstract

BACKGROUND

A growing body of research suggests that regular consumption of dairy foods may counteract obesity and other components of the metabolic syndrome. However, human intervention trials are lacking. We aimed to determine the cardiometabolic health effects of increasing the consumption of reduced fat dairy foods in adults with habitually low dairy intakes in the absence of energy restriction.

METHODS

An intervention trial was undertaken in 61 overweight or obese adults who were randomly assigned to a high dairy diet (HD, 4 serves of reduced fat dairy/day) or a low dairy control diet (LD, ≤1 serve/day) for 6 months then crossed over to the alternate diet for a further 6 months. A range of anthropometric and cardiometabolic parameters including body composition, metabolic rate, blood lipids, blood pressure and arterial compliance were assessed at the end of each diet phase.

RESULTS

Total energy intake was 1120 kJ/day higher during the HD phase, resulting in slight weight gain during this period. However, there were no significant differences between HD and LD in absolute measures of waist circumference, body weight, fat mass or any other cardiometabolic parameter.

CONCLUSION

Recommended intakes of reduced fat dairy products may be incorporated into the diet of overweight adults without adversely affecting markers of cardiometabolic health.

TRIAL REGISTRATION

The trial was registered with the Australia and New Zealand Clinical Trials Registry (ACTRN12608000538347) on 24th October, 2008.

摘要

背景

越来越多的研究表明,经常食用乳制品可能有助于预防肥胖和代谢综合征的其他组成部分。然而,目前缺乏人体干预试验。我们旨在确定在习惯性低乳制品摄入量的成年人中增加低脂肪乳制品的摄入量对心血管代谢健康的影响,且不限制能量摄入。

方法

在 61 名超重或肥胖成年人中进行了一项干预试验,他们被随机分配到高乳制品饮食组(HD,每天 4 份低脂乳制品)或低乳制品对照组(LD,每天≤1 份),持续 6 个月,然后交叉到另一种饮食方案,再持续 6 个月。在每个饮食阶段结束时,评估了一系列人体测量和心血管代谢参数,包括身体成分、代谢率、血脂、血压和动脉顺应性。

结果

HD 期间的总能量摄入量每天增加 1120kJ,在此期间体重略有增加。然而,HD 和 LD 组在腰围、体重、体脂肪或任何其他心血管代谢参数的绝对测量值方面没有显著差异。

结论

建议将低脂乳制品纳入超重成年人的饮食中,而不会对心血管代谢健康的标志物产生不利影响。

试验注册

该试验于 2008 年 10 月 24 日在澳大利亚和新西兰临床试验注册中心(ACTRN12608000538347)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee2/3348063/43b5e69ec656/1743-7075-9-19-1.jpg

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