Department of Soongsil University, Seoul 156-743, Korea.
Chem Commun (Camb). 2012 May 4;48(35):4205-7. doi: 10.1039/c2cc30679d. Epub 2012 Mar 23.
The intracellular glutathione-triggered release of the anticancer drug topotecan from gold nanoparticles in serum-containing media was directly monitored in real time using a label-free fluorescence live-cell imaging technique.
利用无标记荧光活细胞成像技术,直接实时监测含血清介质中金纳米粒子中细胞内谷胱甘肽触发的抗癌药物拓扑替康的释放。