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在含血清介质中，通过金纳米粒子实时监测谷胱甘肽触发的抗癌药物拓扑替康的释放。

Live-cell monitoring of the glutathione-triggered release of the anticancer drug topotecan on gold nanoparticles in serum-containing media.

机构信息

Department of Soongsil University, Seoul 156-743, Korea.

出版信息

Chem Commun (Camb). 2012 May 4;48(35):4205-7. doi: 10.1039/c2cc30679d. Epub 2012 Mar 23.

DOI:10.1039/c2cc30679d
PMID:22441353
Abstract

The intracellular glutathione-triggered release of the anticancer drug topotecan from gold nanoparticles in serum-containing media was directly monitored in real time using a label-free fluorescence live-cell imaging technique.

摘要

利用无标记荧光活细胞成像技术，直接实时监测含血清介质中金纳米粒子中细胞内谷胱甘肽触发的抗癌药物拓扑替康的释放。

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