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国际抗体会议第22届年度抗体工程与第9届年度抗体治疗国际会议以及抗体协会2011年年会,2011年12月5日至8日,加利福尼亚州圣地亚哥

IBC's 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society, December 5-8, 2011, San Diego, CA.

作者信息

Nilvebrant Johan, Dunlop D Cameron, Sircar Aroop, Wurch Thierry, Falkowska Emilia, Reichert Janice M, Helguera Gustavo, Piccione Emily C, Brack Simon, Berger Sven

机构信息

School of Biotechnology; Department of Proteomics; Royal Institute of Technology (KTH); AlbaNova University Center; Stockholm, Sweden.

The Scripps Research Institute; La Jolla, CA USA.

出版信息

MAbs. 2012 Mar-Apr;4(2):153-81. doi: 10.4161/mabs.4.2.19495. Epub 2012 Mar 1.

Abstract

The 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics international conferences, and the 2011 Annual Meeting of The Antibody Society, organized by IBC Life Sciences with contributions from The Antibody Society and two Scientific Advisory Boards, were held December 5-8, 2011 in San Diego, CA. The meeting drew ~800 participants who attended sessions on a wide variety of topics relevant to antibody research and development. As a preview to the main events, a pre-conference workshop held on December 4, 2011 focused on antibodies as probes of structure. The Antibody Engineering Conference comprised eight sessions: (1) structure and dynamics of antibodies and their membrane receptor targets; (2) model-guided generation of binding sites; (3) novel selection strategies; (4) antibodies in a complex environment: targeting intracellular and misfolded proteins; (5) rational vaccine design; (6) viral retargeting with engineered binding molecules; (7) the biology behind potential blockbuster antibodies and (8) antibodies as signaling modifiers: where did we go right, and can we learn from success? The Antibody Therapeutics session comprised five sessions: (1)Twenty-five years of therapeutic antibodies: lessons learned and future challenges; (2) preclinical and early stage development of antibody therapeutics; (3) next generation anti-angiogenics; (4) updates of clinical stage antibody therapeutics and (5) antibody drug conjugates and bispecific antibodies.

摘要

由IBC生命科学公司主办、抗体协会及两个科学顾问委员会协办的第22届年度抗体工程会议、第9届年度抗体治疗国际会议以及2011年抗体协会年会于2011年12月5日至8日在加利福尼亚州圣地亚哥市举行。会议吸引了约800名参会者,他们参加了与抗体研发相关的各种主题的会议。作为主要活动的预演,2011年12月4日举行的会前研讨会聚焦于作为结构探针的抗体。抗体工程会议包括八个分会场:(1)抗体及其膜受体靶点的结构与动力学;(2)结合位点的模型引导生成;(3)新型筛选策略;(4)复杂环境中的抗体:靶向细胞内和错误折叠的蛋白质;(5)合理的疫苗设计;(6)用工程化结合分子进行病毒重靶向;(7)潜在重磅抗体背后的生物学原理;(8)作为信号调节剂的抗体:我们哪里做对了,能否从成功中学习?抗体治疗分会场包括五个分会场:(1)治疗性抗体25年:经验教训与未来挑战;(2)抗体治疗的临床前和早期开发;(3)下一代抗血管生成药物;(4)临床阶段抗体治疗的最新进展;(5)抗体药物偶联物和双特异性抗体。

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