Almagro Juan Carlos, Gilliland Gary L, Breden Felix, Scott Jamie K, Sok Devin, Pauthner Matthias, Reichert Janice M, Helguera Gustavo, Andrabi Raiees, Mabry Robert, Bléry Mathieu, Voss James E, Laurén Juha, Abuqayyas Lubna, Barghorn Stefan, Ben-Jacob Eshel, Crowe James E, Huston James S, Johnston Stephen Albert, Krauland Eric, Lund-Johansen Fridtjof, Marasco Wayne A, Parren Paul W H I, Xu Kai Y
CTI-Boston, Pfizer; Boston, MA USA.
Janssen Research & Development, LLC; Spring House, PA USA.
MAbs. 2014 May-Jun;6(3):577-618. doi: 10.4161/mabs.28421. Epub 2014 Mar 3.
The 24th Antibody Engineering & Therapeutics meeting brought together a broad range of participants who were updated on the latest advances in antibody research and development. Organized by IBC Life Sciences, the gathering is the annual meeting of The Antibody Society, which serves as the scientific sponsor. Preconference workshops on 3D modeling and delineation of clonal lineages were featured, and the conference included sessions on a wide variety of topics relevant to researchers, including systems biology; antibody deep sequencing and repertoires; the effects of antibody gene variation and usage on antibody response; directed evolution; knowledge-based design; antibodies in a complex environment; polyreactive antibodies and polyspecificity; the interface between antibody therapy and cellular immunity in cancer; antibodies in cardiometabolic medicine; antibody pharmacokinetics, distribution and off-target toxicity; optimizing antibody formats for immunotherapy; polyclonals, oligoclonals and bispecifics; antibody discovery platforms; and antibody-drug conjugates.
第24届抗体工程与治疗会议汇聚了众多参与者,他们了解了抗体研发的最新进展。该会议由IBC生命科学公司组织,是抗体协会的年会,抗体协会作为科学赞助商。会议设有关于3D建模和克隆谱系描绘的会前研讨会,还包括了一系列与研究人员相关的各种主题会议,包括系统生物学;抗体深度测序和抗体库;抗体基因变异和使用对抗体反应的影响;定向进化;基于知识的设计;复杂环境中的抗体;多反应性抗体和多特异性;癌症中抗体治疗与细胞免疫的界面;心血管代谢医学中的抗体;抗体药代动力学、分布和脱靶毒性;优化免疫治疗的抗体形式;多克隆抗体、寡克隆抗体和双特异性抗体;抗体发现平台;以及抗体药物偶联物。