Larrick James W, Alfenito Mark R, Scott Jamie K, Parren Paul W H I, Burton Dennis R, Bradbury Andrew R M, Lemere Cynthia A, Messer Anne, Huston James S, Carter Paul J, Veldman Trudi, Chester Kerry A, Schuurman Janine, Adams Gregory P, Reichert Janice M
a Panorama Research Institute and Velocity Pharmaceutical Development , South San Francisco , CA , USA.
b EnGen Bio, Inc. , San Mateo , CA , USA.
MAbs. 2016 Nov/Dec;8(8):1425-1434. doi: 10.1080/19420862.2016.1227665. Epub 2016 Aug 24.
Antibody Engineering & Therapeutics, the largest meeting devoted to antibody science and technology and the annual meeting of The Antibody Society, will be held in San Diego, CA on December 11-15, 2016. Each of 14 sessions will include six presentations by leading industry and academic experts. In this meeting preview, the session chairs discuss the relevance of their topics to current and future antibody therapeutics development. Session topics include bispecifics and designer polyclonal antibodies; antibodies for neurodegenerative diseases; the interface between passive and active immunotherapy; antibodies for non-cancer indications; novel antibody display, selection and screening technologies; novel checkpoint modulators / immuno-oncology; engineering antibodies for T-cell therapy; novel engineering strategies to enhance antibody functions; and the biological Impact of Fc receptor engagement. The meeting will open with keynote speakers Dennis R. Burton (The Scripps Research Institute), who will review progress toward a neutralizing antibody-based HIV vaccine; Olivera J. Finn, (University of Pittsburgh School of Medicine), who will discuss prophylactic cancer vaccines as a source of therapeutic antibodies; and Paul Richardson (Dana-Farber Cancer Institute), who will provide a clinical update on daratumumab for multiple myeloma. In a featured presentation, a representative of the World Health Organization's INN expert group will provide a perspective on antibody naming. "Antibodies to watch in 2017" and progress on The Antibody Society's 2016 initiatives will be presented during the Society's special session. In addition, two pre-conference workshops covering ways to accelerate antibody drugs to the clinic and the applications of next-generation sequencing in antibody discovery and engineering will be held on Sunday December 11, 2016.
《抗体工程与治疗学》是专注于抗体科学与技术的规模最大的会议,也是抗体协会的年会,将于2016年12月11日至15日在加利福尼亚州圣地亚哥举行。14场会议中的每场会议都将包括六位行业和学术领军专家的报告。在本次会议预览中,各场会议主席讨论了他们的主题与当前及未来抗体治疗药物开发的相关性。会议主题包括双特异性抗体和设计多克隆抗体;用于神经退行性疾病的抗体;被动免疫疗法与主动免疫疗法的交叉领域;用于非癌症适应症的抗体;新型抗体展示、筛选和筛选技术;新型检查点调节剂/免疫肿瘤学;用于T细胞治疗的工程抗体;增强抗体功能的新型工程策略;以及Fc受体结合的生物学影响。会议将由主旨演讲拉开帷幕,演讲者包括丹尼斯·R·伯顿(斯克里普斯研究所),他将回顾基于中和抗体的HIV疫苗的进展;奥利韦拉·J·芬恩(匹兹堡大学医学院),她将讨论预防性癌症疫苗作为治疗性抗体的来源;以及保罗·理查森(达纳-法伯癌症研究所),他将提供关于达雷木单抗治疗多发性骨髓瘤的临床最新情况。在一场特色报告中,世界卫生组织国际非专利药品名称(INN)专家组的一位代表将对抗体命名发表看法。“2017年值得关注的抗体”以及抗体协会2016年倡议的进展情况将在协会的特别会议上公布。此外,两场会前研讨会将于2016年12月11日星期日举行,主题分别为加速抗体药物进入临床的方法以及下一代测序在抗体发现和工程中的应用。