Marquardt Law, Washington, DC, USA.
MAbs. 2012 Nov-Dec;4(6):648-52. doi: 10.4161/mabs.22221. Epub 2012 Sep 24.
Now in its 23rd and 10th years, respectively, the Antibody Engineering and Antibody Therapeutics conferences are the Annual Meeting of The Antibody Society. The scientific program covers the full spectrum of challenges in antibody research and development from basic science through clinical development. In this preview of the conferences, the chairs provide their thoughts on sessions that will allow participants to track emerging trends in (1) the development of next-generation immunomodulatory antibodies; (2) the complexity of the environment in which antibodies must function; (3) antibody-targeted central nervous system (CNS) therapies that cross the blood brain barrier; (4) the extension of antibody half-life for improved efficacy and pharmacokinetics (PK)/pharmacodynamics (PD); and (5) the application of next generation DNA sequencing to accelerate antibody research. A pre-conference workshop on Sunday, December 2, 2012 will update participants on recent intellectual property (IP) law changes that affect antibody research, including biosimilar legislation, the America Invents Act and recent court cases. Keynote presentations will be given by Andreas Plückthun (University of Zürich), who will speak on engineering receptor ligands with powerful cellular responses; Gregory Friberg (Amgen Inc.), who will provide clinical updates of bispecific antibodies; James D. Marks (University of California, San Francisco), who will discuss a systems approach to generating tumor targeting antibodies; Dario Neri (Swiss Federal Institute of Technology Zürich), who will speak about delivering immune modulators at the sites of disease; William M. Pardridge (University of California, Los Angeles), who will discuss delivery across the blood-brain barrier; and Peter Senter (Seattle Genetics, Inc.), who will present his vision for the future of antibody-drug conjugates. For more information on these meetings or to register to attend, please visit www.IBCLifeSciences.com/AntibodyEng or call 800-390-4078. Members of The Antibody Society and mAbs journal subscribers receive a 20% discount for meeting registration. To obtain this discount, email kdostie@ibcusa.com. mAbs is the official therapeutics journal of The Antibody Society and offers a discounted subscription to Society members for $49.
现在,抗体工程和抗体治疗会议分别进入第 23 年和第 10 年,它们是抗体学会的年度会议。科学计划涵盖了从基础科学到临床开发的抗体研究和开发的各个方面的挑战。在会议预览中,主席们提供了对以下方面的思考,这些方面将使参与者能够跟踪(1)新一代免疫调节抗体的发展;(2)抗体必须发挥作用的环境的复杂性;(3)穿越血脑屏障的抗体靶向中枢神经系统(CNS)疗法;(4)延长抗体半衰期以提高疗效和药代动力学(PK)/药效学(PD);以及(5)下一代 DNA 测序在加速抗体研究中的应用。在 2012 年 12 月 2 日星期日举行的会前研讨会将更新与会者关于影响抗体研究的最近知识产权(IP)法变化的信息,包括生物类似药立法、美国发明法案和最近的法庭案件。主旨演讲者将是 Andreas Plückthun(苏黎世大学),他将介绍用强大的细胞反应工程受体配体;Gregory Friberg(安进公司),他将提供双特异性抗体的临床更新;James D. Marks(加利福尼亚大学旧金山分校),他将讨论生成肿瘤靶向抗体的系统方法;Dario Neri(苏黎世联邦理工学院),他将介绍在疾病部位递呈免疫调节剂;William M. Pardridge(加利福尼亚大学洛杉矶分校),他将讨论穿过血脑屏障的传递;以及 Peter Senter(西雅图遗传学公司),他将展示他对抗体药物偶联物的未来愿景。有关这些会议的更多信息或注册参加会议,请访问 www.IBCLifeSciences.com/AntibodyEng 或致电 800-390-4078。抗体学会成员和 mAbs 杂志订户在会议注册时可享受 20%的折扣。要获得此折扣,请发送电子邮件至 kdostie@ibcusa.com。mAbs 是抗体学会的官方治疗学杂志,为学会成员提供 49 美元的订阅折扣。