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沙眼衣原体的全基因组重组。

Genome-wide recombination in Chlamydia trachomatis.

机构信息

Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Nat Genet. 2012 Mar 28;44(4):364-6. doi: 10.1038/ng.2225.

DOI:10.1038/ng.2225
PMID:22456736
Abstract

A new study reports comparative genomic analysis of 52 geographically diverse strains of Chlamydia trachomatis. The authors reconstruct a genome-wide phylogeny of the species and report extensive genome-wide recombination across multiple lineages of this intracellular bacterial pathogen.

摘要

一项新的研究报告了对 52 株具有地理多样性的沙眼衣原体菌株的比较基因组分析。作者重建了该物种的全基因组系统发育,并报告了这种细胞内细菌病原体的多个谱系中广泛的全基因组重组。

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本文引用的文献

1
Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing.对多种沙眼衣原体菌株的全基因组分析确定了当前临床分型掩盖的系统发育关系。
Nat Genet. 2012 Mar 11;44(4):413-9, S1. doi: 10.1038/ng.2214.
2
Interplay of recombination and selection in the genomes of Chlamydia trachomatis.沙眼衣原体基因组中重组与选择的相互作用。
Biol Direct. 2011 May 26;6:28. doi: 10.1186/1745-6150-6-28.
3
Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L(2)) and D lineages.
沙眼衣原体高分辨率多位点序列分型:提高了低浓度沙眼衣原体 DNA 临床样本的检测结果。
BMC Microbiol. 2021 Jan 18;21(1):28. doi: 10.1186/s12866-020-02077-y.
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Unveiling the Multilocus Sequence Typing (MLST) Schemes and Core Genome Phylogenies for Genotyping .揭示用于基因分型的多位点序列分型(MLST)方案和核心基因组系统发育
Front Microbiol. 2018 Aug 22;9:1854. doi: 10.3389/fmicb.2018.01854. eCollection 2018.
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Culture-independent approaches to chlamydial genomics.非培养方法在衣原体基因组学中的应用。
Microb Genom. 2018 Feb;4(2). doi: 10.1099/mgen.0.000145. Epub 2018 Jan 3.
6
Enrichment by hybridisation of long DNA fragments for Nanopore sequencing.长 DNA 片段杂交富集用于纳米孔测序。
Microb Genom. 2016 Sep 20;2(9):e000087. doi: 10.1099/mgen.0.000087. eCollection 2016 Sep.
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Rapid detection and strain typing of Chlamydia trachomatis using a highly multiplexed microfluidic PCR assay.使用高度多重微流控PCR检测法快速检测沙眼衣原体并进行菌株分型
PLoS One. 2017 May 31;12(5):e0178653. doi: 10.1371/journal.pone.0178653. eCollection 2017.
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(C) Gene Transfer between Strains Occurs by Homologous Recombination after Co-infection: Implications for Spread of Tetracycline-Resistance among .(C) 共感染后菌株间的基因转移通过同源重组发生:对四环素抗性在……之间传播的影响
Front Microbiol. 2017 Feb 7;8:156. doi: 10.3389/fmicb.2017.00156. eCollection 2017.
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Chlamydia trachomatis from Australian Aboriginal people with trachoma are polyphyletic composed of multiple distinctive lineages.来自患有沙眼的澳大利亚原住民的沙眼衣原体是多系的,由多个独特的谱系组成。
Nat Commun. 2016 Feb 25;7:10688. doi: 10.1038/ncomms10688.
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Genome sequencing of recent clinical Chlamydia trachomatis strains identifies loci associated with tissue tropism and regions of apparent recombination.对近期临床分离的沙眼衣原体菌株进行基因组测序,鉴定出与组织嗜性和明显重组区域相关的基因座。
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J Bacteriol. 2007 Feb;189(3):991-1003. doi: 10.1128/JB.00845-06. Epub 2006 Nov 22.
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Evolution of Chlamydia trachomatis diversity occurs by widespread interstrain recombination involving hotspots.沙眼衣原体多样性的演变是通过涉及热点的广泛株间重组而发生的。
Genome Res. 2007 Jan;17(1):50-60. doi: 10.1101/gr.5674706. Epub 2006 Nov 7.
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Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis.人类专性胞内病原体沙眼衣原体的基因组序列。
Science. 1998 Oct 23;282(5389):754-9. doi: 10.1126/science.282.5389.754.