Department of Pathology and Laboratory Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon SK, Canada S7N 0W8.
Gastroenterol Res Pract. 2012;2012:432517. doi: 10.1155/2012/432517. Epub 2012 Feb 14.
Background. In 1897, Dieulafoy was the first to characterize a gaping arteriole within the gastric mucosa causing massive hematemesis, designating it as "exulceratio simplex." A hundred years later, this vascular abnormality, now commonly referred to as a "Dieulafoy lesion," has been identified through the entire gastrointestinal tract and the bronchus. Objectives and Methods. As the original findings have been subjected to revisions and modifications by modern authors, Dieulafoy's original paper was reviewed and analyzed. The evolution of the current usage of "Dieulafoy's lesion" in the literature has been summarized with comparisons to the original report. Additionally, an index case of a 10-year-old female with a gastric "exulceratio simplex" is reported with a review of previously reported paediatric Dieulafoy lesions. Conclusions. The term "Dieulafoy lesion" in modern literature no longer adheres to the initial conclusions with regards to its origin, demographics, and presenting symptoms. Dieulafoy lesions remain a rare cause of gastrointestinal bleeding that can cause life-threatening haemorrhages in children.
1897 年，迪厄拉富瓦首次描述了胃黏膜内存在一处开放性小动脉，导致大量呕血，并将其命名为“单纯性溃疡”。一个世纪后，这种血管异常，现在通常被称为“迪厄拉富瓦病变”，已在整个胃肠道和支气管中被发现。
由于现代作者对原始发现进行了修订和修改，因此对迪厄拉富瓦的原始论文进行了回顾和分析。总结了文献中“迪厄拉富瓦病变”的当前用法的演变，并与原始报告进行了比较。此外，还报告了一例 10 岁女性胃“单纯性溃疡”的病例，并回顾了以前报道的儿科迪厄拉富瓦病变。
现代文献中的“迪厄拉富瓦病变”一词不再符合其起源、人口统计学和临床表现的最初结论。迪厄拉富瓦病变仍然是胃肠道出血的罕见原因，可导致儿童发生危及生命的出血。
