Hallén A, Ljunghall K, Wallin J
Department of Dermatology and Venereology, University Hospital, Uppsala, Sweden.
Genitourin Med. 1987 Oct;63(5):316-9. doi: 10.1136/sti.63.5.316.
Removal of genital warts by thermocautery was performed in 108 patients (57 men and 51 women) under topical anaesthesia with a local anaesthetic cream, lidocaine and prilocaine (EMLA). Most men had warts in the preputial cavity, most women had warts situated on the mucous membranes of the vulva, and warts at multiple sites were common. About 1 ml of cream per lesion was applied to the warts for 20 to 105 minutes before the operation. Plastic film (Glad, Union Carbide) was applied over the cream when natural occlusion, such as under the prepuce or on the introitus, was not present. Local pallor was seen in 30% of the patients, redness in 53%, and oedema in 15%, but did not cause any discomfort and were clinically insignificant. Analgesia was sufficient in 96% of the men and in 40% of the women. Additional local infiltration was given to 60% of the women, but was not as painful as injections generally are in the genital area. The analgesic efficacy on women may be further improved by optimising the application time on the genital mucosa.
108例患者（57例男性和51例女性）在使用局部麻醉乳膏利多卡因和丙胺卡因（EMLA）进行局部麻醉的情况下，通过热灼术去除尖锐湿疣。大多数男性的疣体位于包皮腔内，大多数女性的疣体位于外阴黏膜，疣体多发的情况很常见。术前，每个疣体涂抹约1毫升乳膏，持续20至105分钟。若不存在自然封闭情况，如包皮下或阴道口处，则在乳膏上覆盖塑料薄膜（Glad，联合碳化物公司）。30%的患者出现局部苍白，53%出现发红，15%出现水肿，但均未引起任何不适，临床上无显著意义。96%的男性和40%的女性镇痛效果良好。60%的女性进行了额外的局部浸润麻醉，但并不像生殖器部位一般的注射那样疼痛。通过优化在生殖器黏膜上的涂抹时间，对女性的镇痛效果可能会进一步提高。
