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自由基和抗氧化防御在口腔相关疾病中的作用。

Role of free radicals and antioxidant defences in oral cavity-related pathologies.

机构信息

Department of Physiology, School of Medicine, University of Kentucky Medical Center, Lexington, KY 40536-0298, USA.

出版信息

J Oral Pathol Med. 2012 Oct;41(9):649-61. doi: 10.1111/j.1600-0714.2012.01143.x. Epub 2012 Apr 12.

DOI:10.1111/j.1600-0714.2012.01143.x
PMID:22494322
Abstract

Free radicals play a key role in the development of several pathological conditions. Therefore, several methods have been developed to measure oxidative stress from bodily fluids including blood, urine and, more recently, saliva. Free radical and antioxidant defences within the oral cavity may play a key role in odontostomatological pathologies. This review provides an update of the literature concerning the association of oxidative stress with pathological conditions associated with the oral cavity. It focuses on the diagnostic and therapeutic importance of the tests based on saliva specimens in a preventive perspective.

摘要

自由基在几种病理状况的发展中起着关键作用。因此,已经开发了几种方法来测量包括血液、尿液在内的体液中的氧化应激,最近,还包括唾液。口腔内的自由基和抗氧化防御可能在牙病学病理中起着关键作用。本综述提供了有关氧化应激与口腔相关病理状况之间关联的文献更新。它侧重于基于唾液样本的测试在预防方面的诊断和治疗重要性。

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