Department of Organic and Industrial Chemistry, University of Parma, Parma, Italy.
Mol Nutr Food Res. 2012 Apr;56(4):632-40. doi: 10.1002/mnfr.201100515.
The main objectives of this study were to estimate dietary fumonisin exposure and nutrient intake in a group of patients diagnosed with celiac disease compared to non-celiac subjects.
The fumonisin level in 118 frequently consumed corn-based products was determined and dietary habits were recorded using a 7-day weighed food record. Data were then compared to those obtained for a control group. The fumonisin intake in the celiac patients was significantly higher than in controls, with mean values (± SE) of 0.395 ± 0.049 and 0.029 ± 0.006 μg/kg body weight per day, respectively. With regard to nutritional habits, celiac patients showed a preference for a high fat diet, coupled with a high intake of sweets and soft drinks and a low intake of vegetables, iron, calcium and folate.
These findings may have serious health implications for the celiac population due to the widespread occurrence of fumonisins in most of the widely consumed gluten-free products, leading to continuous exposure to this particular mycotoxin. Moreover, the recorded nutritional quality of the celiac patient's diet raises concerns regarding its long-term adequacy and its potential impact on chronic conditions such as type 2 diabetes and cardiovascular diseases.
本研究的主要目的是估计一组乳糜泻患者与非乳糜泻患者的膳食伏马菌素暴露和营养素摄入量。
测定了 118 种经常食用的玉米基产品中的伏马菌素水平，并使用 7 天称重食物记录来记录饮食习惯。然后将数据与对照组的数据进行比较。乳糜泻患者的伏马菌素摄入量明显高于对照组，平均值（± SE）分别为 0.395 ± 0.049 和 0.029 ± 0.006 μg/kg 体重/天。关于营养习惯，乳糜泻患者喜欢高脂肪饮食，同时摄入大量甜食和软饮料，而蔬菜、铁、钙和叶酸的摄入量较低。
由于大多数广泛食用的无麸质产品中都普遍存在伏马菌素，因此这些发现可能对乳糜泻人群的健康产生严重影响，导致持续接触这种特定的霉菌毒素。此外，记录的乳糜泻患者饮食的营养质量令人担忧，因为其长期充足性及其对 2 型糖尿病和心血管疾病等慢性疾病的潜在影响。
