Department of Psychiatry and Human Behavior, Brown University School of Medicine, Rhode Island Hospital, Providence, RI, USA.
Compr Psychiatry. 2012 Oct;53(7):940-5. doi: 10.1016/j.comppsych.2012.02.008. Epub 2012 Apr 11.
The DSM-5 Work Group for Personality and Personality Disorders (PDs) recommended retaining 6 specific PD "types" (antisocial, avoidant, borderline, narcissistic, obsessive-compulsive, and schizotypal) and eliminating the other 4 PDs currently included in DSM-IV (paranoid, schizoid, histrionic, and dependent). One important clinical aspect of PDs is their association with indices of psychosocial morbidity. Because the literature on the relationship between PDs and psychosocial morbidity in psychiatric patients is limited, we undertook the current analysis of the Rhode Island Methods to Improve Diagnostic Assessment and Services project database to examine which PDs were most strongly associated with a variety of measures of psychosocial morbidity. We tested the hypothesis that the disorders recommended for retention in DSM-5 would be associated with more severe morbidity than the disorders recommended for deletion. A total of 2150 psychiatric outpatients were evaluated with semistructured diagnostic interviews for DSM-IV Axes I and II disorders and 7 measures of psychosocial morbidity. We examined the correlation between each PD dimensional score and each measure of morbidity and then conducted multiple regression analyses to determine which PDs were independently associated with the indices of morbidity. For the 6 PDs proposed for retention in DSM-5, 36 (85.7%) of the 42 correlations were significant, whereas for the 4 PDs proposed for deletion, 26 (92.9%) of the 28 correlations were significant. In the regression analyses for the 6 PDs proposed for retention in DSM-5, 19 (45.2%) of the 42 β coefficients were significant, whereas for the 4 PDs proposed for deletion, 7 (25.0%) of the 28 β coefficients were significant. The results of the present study, along with the results of other studies, do not provide clear evidence for the preferential retention of some PDs over others based on their association with indices of psychosocial morbidity.
DSM-5 人格和人格障碍(PD)工作组建议保留 6 种特定的 PD“类型”(反社会、回避、边缘、自恋、强迫和分裂型),并消除目前 DSM-IV 中包含的另外 4 种 PD(偏执、分裂型、表演和依赖型)。PD 的一个重要临床方面是它们与心理社会发病率的指标有关。由于关于精神病患者 PD 与心理社会发病率之间关系的文献有限,我们对罗德岛改善诊断评估和服务项目数据库进行了当前分析,以检查哪些 PD 与各种心理社会发病率指标的相关性最强。我们检验了这样一个假设,即在 DSM-5 中建议保留的障碍与更严重的发病率有关,而在 DSM-5 中建议删除的障碍与更严重的发病率有关。共有 2150 名精神科门诊患者接受了 DSM-IV 轴 I 和 II 障碍的半结构化诊断访谈和 7 项心理社会发病率测量。我们检查了每个 PD 维度得分与每种发病率测量之间的相关性,然后进行了多元回归分析,以确定哪些 PD 与发病率指数独立相关。对于建议保留在 DSM-5 中的 6 种 PD,42 个相关中的 36 个(85.7%)具有统计学意义,而对于建议删除的 4 种 PD,28 个相关中的 26 个(92.9%)具有统计学意义。在建议保留在 DSM-5 中的 6 种 PD 的回归分析中,42 个β系数中有 19 个(45.2%)具有统计学意义,而对于建议删除的 4 种 PD,28 个β系数中有 7 个(25.0%)具有统计学意义。本研究的结果,以及其他研究的结果,并没有提供明确的证据表明,根据 PD 与心理社会发病率指标的相关性,某些 PD 比其他 PD 更优先保留。