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通过开-关-开荧光开关促进菁染料的功能化，用于成像细胞和组织中的 H2O2 氧化应激和巯基还原修复。

Facilitative functionalization of cyanine dye by an on-off-on fluorescent switch for imaging of H2O2 oxidative stress and thiols reducing repair in cells and tissues.

机构信息

School of Chemical Engineering, Dalian University of Technology, Dalian, PR China.

出版信息

Chem Commun (Camb). 2012 May 21;48(41):4980-2. doi: 10.1039/c2cc30985h. Epub 2012 Apr 12.

DOI:10.1039/c2cc30985h
PMID:22499337
Abstract

We presented the design, synthesis, spectroscopy, and biological applications of DA-Cy, an on-off-on fluorescent probe to monitor H(2)O(2) oxidative stress and thiols reducing repair in living cells and tissues simply and directly.

摘要

我们介绍了 DA-Cy 的设计、合成、光谱学特性以及在活细胞和组织中监测 H(2)O(2)氧化应激和巯基还原修复的应用，DA-Cy 是一种开-关-开型荧光探针，其应用简单、直接。

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