肯尼亚北部游牧牧民的狗是具有质粒介导头孢菌素和喹诺酮耐药性的大肠杆菌的储主，包括大流行克隆 B2-O25-ST131。
Dogs of nomadic pastoralists in northern Kenya are reservoirs of plasmid-mediated cephalosporin- and quinolone-resistant Escherichia coli, including pandemic clone B2-O25-ST131.
机构信息
Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.
出版信息
Antimicrob Agents Chemother. 2012 Jul;56(7):4013-7. doi: 10.1128/AAC.05859-11. Epub 2012 Apr 16.
Abstract
Resistance in Escherichia coli isolates colonizing gastrointestinal tracts of dogs, cats, and their owners in Northern Kenya was investigated with an emphasis on extended-spectrum beta-lactamases (ESBLs). Totals of 47 (22%, n = 216), 2 (4%, n = 50), and 4 (17%, n = 23) CTX-M-15-producing E. coli isolates were obtained from dogs, cats, and humans, respectively. CTX-M-15-producing E. coli isolates with identical PFGE profiles were detected in animals and humans living in the same area.
摘要
在肯尼亚北部，研究了定植于狗、猫及其主人胃肠道的大肠杆菌分离株的耐药性，重点研究了产超广谱β-内酰胺酶（ESBLs）的情况。从狗、猫和人中共获得了 47 株（22%，n=216）、2 株（4%，n=50）和 4 株（17%，n=23）CTX-M-15 产大肠埃希菌。在同一地区生活的动物和人类中检测到具有相同 PFGE 图谱的 CTX-M-15 产大肠埃希菌。
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