Hennekens C H, Willett W, Rosner B, Cole D S, Mayrent S L
JAMA. 1979 Nov 2;242(18):1973-4.
For a series of 568 married men who died of coronary heart disease and an equal number of matched control subjects, information was collected on a large number of variables, including daily alcohol consumption classified by type of beverage, namely, beer, wine, or liquor. Daily consumption of small to moderate amounts of alcohol (2 oz [59.2mL] or less daily) was inversely related to coronary death. This inverse relation was present in both crude and adjusted matched-pair analyses and was similar for each type of alcohol, as indicated by adjusted relative risks of 0.3 for beer, 0.3 for wine, and 0.2 for liquor. In contrast, for heavy drinking, there was no association with coronary death in either crude or adjusted analyses.
对568名死于冠心病的已婚男性以及数量相等的匹配对照对象进行了研究，收集了大量变量信息，包括按饮料类型分类的每日酒精摄入量，即啤酒、葡萄酒或烈酒。每日少量至适量饮酒（每日2盎司[59.2毫升]或更少）与冠心病死亡呈负相关。这种负相关在粗匹配对分析和调整后的匹配对分析中均存在，并且每种酒精类型的情况相似，调整后的相对风险显示，啤酒为0.3，葡萄酒为0.3，烈酒为0.2。相比之下，对于大量饮酒，在粗分析或调整分析中均未发现与冠心病死亡有关联。
