Oramasionwu Christine U, Hunter Jonathan M, Brown Carolyn M, Morse Gene D, Lawson Kenneth A, Koeller Jim M, Frei Christopher R
University of North Carolina, UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA.
Open AIDS J. 2012;6:29-35. doi: 10.2174/1874613601206010029. Epub 2012 Apr 26.
Blacks in the United States bear a disproportionate burden of Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) and cardiovascular disease (CVD). It has been demonstrated that HIV/AIDS itself and HIV/AIDS-related therapies may predispose patients to early onset of CVD. It is also possible that Black patients may be at greater risk for this interaction. Thus, the objective of this literature review was to identify and critically evaluate disparities in CVD between Black and White patients with HIV/AIDS.
A MEDLINE search (January 1, 1950 to May 31, 2010) was performed to identify original research articles published in the English language. The search was limited to articles that evaluated race-based disparities for CVD among patients with HIV/AIDS.
Of the five publications included in this review, a CVD diagnosis was the primary focus for only three of the studies and was a secondary objective for the remaining two studies. Two studies concluded that Blacks were more likely than Whites to have a CVD diagnosis at time of hospital admission, whereas, the other three studies did not detect any race-based disparities.
Few studies have addressed the issue of Black race, HIV/AIDS, and CVD, highlighting the need for future research in this area.
美国黑人承受着不成比例的人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征（AIDS）和心血管疾病（CVD）负担。已有研究表明，HIV/AIDS本身及与HIV/AIDS相关的治疗可能使患者易患早期CVD。黑人患者也可能在这种相互作用中面临更大风险。因此，本综述的目的是识别并严格评估HIV/AIDS黑人患者与白人患者在CVD方面的差异。
进行了一次MEDLINE检索（1950年1月1日至2010年5月31日），以识别用英文发表的原创研究文章。检索仅限于评估HIV/AIDS患者中基于种族的CVD差异的文章。
在本综述纳入的五篇出版物中，只有三项研究将CVD诊断作为主要关注点，其余两项研究将其作为次要目标。两项研究得出结论，黑人在入院时比白人更有可能被诊断患有CVD，而其他三项研究未发现任何基于种族的差异。
很少有研究涉及黑人种族、HIV/AIDS和CVD问题，这凸显了该领域未来研究的必要性。
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