Department of Chemistry, Division of Biochemistry, Faculty of Science, University of Kahramanmaraş Sütçü İmam, 46100 Kahramanmaraş, Turkey.
Mediators Inflamm. 2012;2012:619293. doi: 10.1155/2012/619293. Epub 2012 Apr 23.
Maraş powder (MP), a different type of smokeless tobacco (ST) and prepared from a tobacco of species Nicotiana rustica Linn, is widely used in Turkey. We aimed to investigate the effects of MP on salivary total sialic acid (TSA) and malondialdehyde (MDA) levels and to compare these parameters in smokers and MP users (MPUs). The salivary TSA and MDA concentrations were significantly higher in the smokers and MPU than those of control subjects and also in MPU than that of smokers. We have also observed that as the number of cigarettes consumed and MP amount increases, TSA and MDA levels increase too. In smokers, MDA values were significantly correlated with the number of cigarettes smoked and the duration of smoking. In MPU, both MDA and TSA levels were significantly correlated with the duration of MP use and the amount of daily consumed MP. We have concluded increased salivary TSA and MDA levels associated in MPU and smokers. Results can help to evaluate harmful effects of these habits. It is important to point out that bigger change in the measured parameters has been observed for MP use. This observation may be an important indication of harmful effects of ST use as MP.
马拉什粉（MP）是一种不同类型的无烟烟草（ST），由烟草品种Nicotiana rustica Linn 制成，在土耳其广泛使用。我们旨在研究 MP 对唾液总唾液酸（TSA）和丙二醛（MDA）水平的影响，并比较吸烟者和 MP 用户（MPU）的这些参数。与对照组相比，吸烟者和 MPU 者的唾液 TSA 和 MDA 浓度明显更高，MPU 者的唾液 TSA 和 MDA 浓度也明显高于吸烟者。我们还观察到，随着香烟消费量和 MP 用量的增加，TSA 和 MDA 水平也随之增加。在吸烟者中，MDA 值与吸烟的支数和吸烟时间呈显著相关。在 MPU 中，MDA 和 TSA 水平均与 MP 使用时间和每日消耗 MP 的量呈显著相关。我们得出结论，MPU 和吸烟者的唾液 TSA 和 MDA 水平升高。这些结果有助于评估这些习惯的有害影响。需要指出的是，与吸烟相比，MP 用量的测量参数变化更大。这一观察结果可能是 ST 使用有害影响的一个重要迹象，就像 MP 一样。
