胰腺癌的流行病学和家族史的作用。
Epidemiology of pancreatic cancer and the role of family history.
机构信息
Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
出版信息
J Surg Oncol. 2013 Jan;107(1):1-7. doi: 10.1002/jso.23149. Epub 2012 May 15.
Abstract
Pancreatic cancer is a lethal disease for which only a small number of risk factors have been identified. In addition to older age, male gender, and black race, risk factors include smoking, obesity, long-standing diabetes and pancreatitis, and heavy alcohol use; allergies such as hay fever are related to lowered risk. Several genetic syndromes increase risk of pancreatic cancer. Work on more common genetic variants promises to reveal more potentially important genetic associations.
摘要
胰腺癌是一种致命的疾病，目前仅发现少数几种风险因素。除了年龄较大、男性、黑种人以外，风险因素还包括吸烟、肥胖、长期糖尿病和胰腺炎、大量饮酒；花粉热等过敏与降低风险有关。几种遗传综合征会增加胰腺癌的风险。对更常见的遗传变异的研究有望揭示更多潜在的重要遗传关联。
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