Trehan Indi, O'Hare Bernadette A, Phiri Ajib, Heikens Geert Tom
Department of Paediatrics & Child Health, University of Malawi College of Medicine, Private Bag 360, Chichiri 3, Blantyre, Malawi.
AIDS Res Treat. 2012;2012:790786. doi: 10.1155/2012/790786. Epub 2012 Mar 1.
Infection with HIV, and oftentimes coinfection with TB, complicates the care of severely malnourished children in sub-Saharan Africa. These superimposed infections challenge clinicians faced with a population of malnourished children for whose care evidence-based guidelines have not kept up. Even as the care of HIV-uninfected malnourished children has improved dramatically with the advent of community-based care and even as there are hopeful signs that the HIV epidemic may be stabilizing or ameliorating, significant gaps remain in the care of malnourished children with HIV. Here we summarize what is currently known, what remains unknown, and what remains challenging about how to treat severely malnourished children with HIV and TB.
感染艾滋病毒，且往往同时感染结核病，使撒哈拉以南非洲地区严重营养不良儿童的护理变得复杂。这些叠加感染给面对营养不良儿童群体的临床医生带来了挑战，因为针对该群体护理的循证指南并未跟上实际情况。即便随着社区护理的出现，未感染艾滋病毒的营养不良儿童的护理有了显著改善，即便有令人鼓舞的迹象表明艾滋疫情可能正在稳定或缓解，但在感染艾滋病毒的营养不良儿童的护理方面仍存在重大差距。在此，我们总结了目前已知的、仍未知的以及在如何治疗感染艾滋病毒和结核病的严重营养不良儿童方面仍具挑战性的问题。
