2011 年，南非一名免疫功能低下婴儿感染疫苗衍生脊髓灰质炎 3 型病毒。
Immunodeficiency-associated vaccine-derived poliovirus type 3 in infant, South Africa, 2011.
机构信息
National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.
出版信息
Emerg Infect Dis. 2012 Jun;18(6):992-4. doi: 10.3201/eid1806.120037.
Abstract
Patients with primary immunodeficiency are prone to persistently excrete Sabin-like virus after administration of live-attenuated oral polio vaccine and have an increased risk for vaccine-derived paralytic polio. We report a case of type 3 immunodeficiency-associated vaccine-derived poliovirus in a child in South Africa who was born with X-linked immunodeficiency syndrome.
摘要
原发性免疫缺陷患者在服用口服脊髓灰质炎减毒活疫苗后易持续排出沙宾样病毒，并且发生疫苗衍生的麻痹性脊髓灰质炎的风险增加。我们报告了南非一名 X 连锁免疫缺陷综合征患儿发生 3 型免疫缺陷相关疫苗衍生脊髓灰质炎病毒的病例。
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