Sakai Yuji, Tsuyuguchi Toshio, Sugiyama Harutoshi, Nishikawa Takao, Kurosawa Jo, Saito Masayoshi, Tawada Katsunobu, Mikata Rintaro, Tada Motohisa, Ishihara Takeshi, Yokosuka Osamu
Department of Medicine and Clinical Oncology, Chiba University, Japan.
Hepatogastroenterology. 2013 Jan-Feb;60(121):58-64. doi: 10.5754/hge12351.
BACKGROUND/AIMS: Recently, there have been sporadic reports of lithotomy using endoscopic sphincterotomy combined with large balloon dilation (EPLBD) against large or multiple bile duct stones. However, there are not many reports so far concerning this procedure. Therefore, we decided to discuss the results of EPLBD against large or multiple bile duct stones.
Stone retrieval using EPLBD was performed with 59 patients of choledocholithiasis, A) with 13 mm or more in shortest dimension, or B) multiple (≥3) bile duct stones, with the smallest more than 10 mm in shortest dimension. The papilla treated with endoscopic sphincterotomy (EST) was dilated using a 12-20 mm balloon suitable for the biliary ductal size.
The success rate for the first lithotomy for choledocholithiasis was 83.1% (49/59). The final lithotomy rate was 100% (59/59). The time required for lithotomy was 43.7 (12-125) minutes and the number of treatment was 1.3 (1-4) on average. Lithotripsy was needed in 13.6% (8/59). The incidence of coincidental events associated with the procedure was 6.8% (4/59). No pancreatitis was noted.
An endoscopic treatment using EST plus large balloon dilation against large or multiple bile duct stones was suggested to be safe and effective.
背景/目的:最近,有零星报道称采用内镜括约肌切开术联合大球囊扩张术(EPLBD)治疗肝外胆管大结石或多发结石。然而,目前关于该手术的报道并不多。因此,我们决定探讨EPLBD治疗肝外胆管大结石或多发结石的效果。
对59例胆总管结石患者采用EPLBD取石,这些患者的结石情况为:A)最短径≥13mm,或B)多发(≥3枚)胆管结石,最小结石最短径>10mm。使用适合胆管大小的12 - 20mm球囊对经内镜括约肌切开术(EST)处理后的乳头进行扩张。
胆总管结石首次取石成功率为83.1%(49/59)。最终取石率为100%(59/59)。取石所需时间为43.7(12 - 125)分钟,平均治疗次数为1.3(1 - 4)次。13.6%(8/59)的患者需要进行碎石。该手术相关并发症发生率为6.8%(4/59)。未发现胰腺炎病例。
EST联合大球囊扩张术治疗肝外胆管大结石或多发结石的内镜治疗方法安全有效。