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海洋天然产物:新药的来源。

Marine natural products: a way to new drugs.

机构信息

Pacific Institute of Bioorganic Chemistry, Far-eastern Branch of the Russian Academy of Science.

出版信息

Acta Naturae. 2009 Jul;1(2):15-25.

PMID:22649599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3347521/
Abstract

The investigation of marine natural products (low molecular weight bioregulators) is a rapidly developing scientific field at the intersection of biology and chemistry. Investigations aimed at detecting, identifying, and understanding the structure of marine natural products have led to the discovery of 20,000 new substances, including those characterized by an extremely high physiological activity. Some results and prospects of works aimed at creating new drugs on the basis of marine natural products are discussed herein.

摘要

海洋天然产物(低分子量生物调节剂)的研究是生物学和化学交叉领域中迅速发展的科学领域。旨在检测、鉴定和了解海洋天然产物结构的研究导致了 20000 种新物质的发现,其中包括具有极高生理活性的物质。本文讨论了基于海洋天然产物创造新药的工作的一些结果和前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/49c0e47843b3/AN20758251-02-015-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/07a7c92e9ded/AN20758251-02-015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/62f05d5e1aca/AN20758251-02-015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/38dc10425973/AN20758251-02-015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/ae5407ca897d/AN20758251-02-015-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/8c909bb9f096/AN20758251-02-015-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/8fa23db006f5/AN20758251-02-015-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/cae24f7fb118/AN20758251-02-015-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/49c0e47843b3/AN20758251-02-015-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/07a7c92e9ded/AN20758251-02-015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/62f05d5e1aca/AN20758251-02-015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/38dc10425973/AN20758251-02-015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/ae5407ca897d/AN20758251-02-015-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/8c909bb9f096/AN20758251-02-015-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/8fa23db006f5/AN20758251-02-015-g006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8058/3347521/49c0e47843b3/AN20758251-02-015-g008.jpg

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