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海洋来源真菌 Aspergillus carneus Blochwitz 的次生代谢产物。

Secondary metabolites from a marine-derived fungus Aspergillus carneus Blochwitz.

机构信息

Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russian Federation.

出版信息

Phytochemistry. 2012 Aug;80:123-31. doi: 10.1016/j.phytochem.2012.05.008. Epub 2012 May 31.

Abstract

Prenylated indole alkaloids, carneamides A-C (1-3), quinazolinone derivatives, carnequinazolines A-C (5-7), aryl C-glycosides, carnemycin A, B (8, 9) and a drimane sesquiterpenoid (10), together with known compounds (11-21) were isolated from the marine-derived fungus Aspergillus carneus (Trichocomaceae) KMM 4638. The antimicrobial and cytotoxic activities of the several alkaloids were examined.

摘要

从海洋来源真菌曲霉菌(Trichocomaceae)KMM 4638 中分离得到了具有取代吲哚生物碱、肉酰胺 A-C(1-3)、喹唑啉酮衍生物、肉喹唑啉 A-C(5-7)、芳基 C-糖苷、肉霉素 A、B(8、9)和一种裂环二萜(10),以及已知化合物(11-21)。对几种生物碱的抗菌和细胞毒性活性进行了检测。

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