Chaudhari Dipak, Sung Eric C, Paranjpe Avina, Jewett Anahid
University of California, Los Angeles School of Dentistry, 90095, USA.
J Calif Dent Assoc. 2012 May;40(5):409-17.
Using ex vivo human tooth, the authors demonstrated that dental pulp stromal cells that survive after placement of composite, mineral trioxide aggregate, and glass ionomer are weaker since they undergo synergistic cell death when exposed to 2-hydroxyethylmethacrylate. DPSCs extracted from teeth that were restored with the combination of composite or MTA or GI with N-acetyl cysteine were protectedfrom cell death. Therefore, application of NAC may protect the DPSCs from adverse effects after tooth restoration.
