氟化石墨烯促进干细胞的神经诱导。
Fluorinated graphene for promoting neuro-induction of stem cells.
机构信息
Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.
出版信息
Adv Mater. 2012 Aug 16;24(31):4285-90. doi: 10.1002/adma.201200846. Epub 2012 Jun 12.
PMID:22689093
Abstract
Surface engineering of substrates offers the possibility of controlling the physiological functions of cells at the molecular level. Fluorinated graphene promotes the differentiation of MSCs towards neuronal lineages. Cell alignment using printed polydimethylsiloxane channel arrays on fluorinated graphene further enhances the neuro-induction of MSCs even in the absence of chemical inducers.
摘要
基底的表面工程提供了在分子水平上控制细胞生理功能的可能性。氟化石墨烯促进间充质干细胞向神经元谱系分化。即使在没有化学诱导剂的情况下，使用氟化石墨烯上印刷的聚二甲基硅氧烷通道阵列进行细胞定向排列，也能进一步增强间充质干细胞的神经诱导。
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