Heller T, Müller N, Kloos C, Wolf G, Müller U A
Department of Medicine III, University Hospital, Jena, Germany.
Exp Clin Endocrinol Diabetes. 2012 Oct;120(9):540-6. doi: 10.1055/s-0032-1311640. Epub 2012 Jun 11.
Patients often use dietary supplements in addition to the therapies prescribed by their physicians. This self medication is often not listed in the drug history. We supposed that people, who are more afraid of co-morbidities or diabetes late complications and who exhibit a higher fear of the potential side effects of prescribed drugs, are more inclined to use dietary supplements.
We checked the use of dietary supplements with a standardised questionnaire in patients treated in a centre for endocrinology and metabolic diseases. Demographic and clinical data were taken from the electronic health record EMIL®.
A total of 428 patients (51.4% women), mean age 58.3 years, completed the standardised questionnaire. Supplements were used by 41%: Mineral nutrients 60.2%, vitamins 56.8%, "other supplements" (e. g. omega-3-fatty acids, antidiabetic agents) 43.1% and medical herbs 35.1%. The users of supplements were predominantly women (p<0.001), non-smokers (p=0.004), persons with frequent medical appointments (p=0.014) and with a negative attitude towards the effectiveness of the physician prescribed medication (p=0.012). Patients with diabetes do not use supplements more often than patients without. The use of dietary supplements was not associated with patients' fear to develop co-morbidities of existing diseases (p=0.132) or a higher fear of side effects of prescribed drugs (p=0.099).
Nearly half of the patients in a centre for endocrinology and metabolic diseases use self medications with dietary supplements. There is no association between the fear of co-morbidities or side effects of physicians prescribed drugs and a self medication with dietary supplements.
患者除了使用医生开的治疗药物外，还经常服用膳食补充剂。这种自我用药情况在用药史中往往未被列出。我们推测，那些更害怕合并症或糖尿病晚期并发症，且对处方药潜在副作用表现出更高恐惧的人，更倾向于使用膳食补充剂。
我们在一家内分泌与代谢疾病中心对患者使用标准化问卷进行了膳食补充剂使用情况的调查。人口统计学和临床数据取自电子健康记录EMIL®。
共有428名患者（51.4%为女性），平均年龄58.3岁，完成了标准化问卷。41%的患者使用补充剂：矿物质营养素60.2%，维生素56.8%，“其他补充剂”（如ω-3脂肪酸、抗糖尿病药物）43.1%，草药35.1%。补充剂使用者主要为女性（p<0.001）、非吸烟者（p=0.004）、经常就医者（p=0.014）以及对医生开的药的疗效持消极态度者（p=0.012）。糖尿病患者使用补充剂的频率并不高于非糖尿病患者。膳食补充剂的使用与患者对现有疾病合并症的恐惧（p=0.132）或对处方药副作用的更高恐惧（p=0.0999）无关。
在内分泌与代谢疾病中心，近一半的患者使用膳食补充剂进行自我用药。对合并症或医生处方药副作用的恐惧与使用膳食补充剂进行自我用药之间没有关联。
