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蒽改性 DNA 内的光控结合和结合控制的光致变色。

Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA.

机构信息

School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

出版信息

J Am Chem Soc. 2012 Jul 4;134(26):10791-4. doi: 10.1021/ja304205m. Epub 2012 Jun 25.

DOI:10.1021/ja304205m
PMID:22694485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3614019/
Abstract

Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.

摘要

经修饰的 DNA 链经历可逆的光诱导反应，涉及两个附加蒽标签的分子内光二聚化。光二聚体对互补链的结合行为表现出明显的差异，这取决于修饰位置之间的碱基数量。通过预形成双链，可以抑制光致变色，说明存在双模门控行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/497894ff8eee/ja-2012-04205m_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/b709e959ba8a/ja-2012-04205m_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/b0d29dcbd0fe/ja-2012-04205m_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/8977deead4f0/ja-2012-04205m_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/488837824ee0/ja-2012-04205m_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/2d98367cb80d/ja-2012-04205m_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/497894ff8eee/ja-2012-04205m_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/b709e959ba8a/ja-2012-04205m_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/b0d29dcbd0fe/ja-2012-04205m_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/8977deead4f0/ja-2012-04205m_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/488837824ee0/ja-2012-04205m_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/2d98367cb80d/ja-2012-04205m_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4991/3614019/497894ff8eee/ja-2012-04205m_0009.jpg

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2
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Bioorg Med Chem Lett. 2012 Jan 1;22(1):129-32. doi: 10.1016/j.bmcl.2011.11.053. Epub 2011 Nov 20.
3
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Electroporation and microinjection successfully deliver single-stranded and duplex DNA into live cells as detected by FRET measurements.通过荧光共振能量转移（FRET）测量检测发现，电穿孔和显微注射成功地将单链和双链DNA导入活细胞。
PLoS One. 2014 Apr 22;9(4):e95097. doi: 10.1371/journal.pone.0095097. eCollection 2014.
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5
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