Dipartimento di Scienze del Suolo, della Pianta, dell'Ambiente e delle Produzioni Animali (DISSPAPA), Università di Napoli Federico II, Via Università 100, 80055 Portici, Italy.
J Nat Prod. 2012 Jun 22;75(6):1130-7. doi: 10.1021/np300200j. Epub 2012 Jun 13.
A new phytotoxic geranylcyclohexenetriol, named phomentrioloxin, was isolated from the liquid culture of Phomopsis sp., a fungal pathogen proposed for the biological control of Carthamus lanatus, a widespread and troublesome thistle weed belonging to the Asteraceae family causing severe crop and pastures losses in Australia. The structure of phomentrioloxin was established by spectroscopic, X-ray, and chemical methods as (1S,2S,3S,4S)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)cyclohex-5-ene-1,2,4-triol. At a concentration of 6.85 mM, the toxin causes the appearance of necrotic spots when applied to leaves of both host and nonhost plants. It also causes growth and chlorophyll content reduction of fronds of Lemna minor and inhibition of tomato rootlet elongation. Finally, in preliminary bioassays, phomentrioloxin did not show any antibacterial, fungicidal, or zootoxic activities.
一种新的植物毒性香叶基环己三醇，命名为 phomentrioloxin，从真菌病原菌 Phomopsis sp. 的液体培养物中分离得到，该病原菌被提议用于生物防治广泛且麻烦的菊科蓟属杂草——矢车菊，这种杂草在澳大利亚造成严重的作物和牧场损失。phomentrioloxin 的结构通过光谱、X 射线和化学方法确定为（1S,2S,3S,4S）-3-甲氧基-6-（7-甲基-3-亚甲基-辛-6-烯-1-炔基）环己-5-烯-1,2,4-三醇。在 6.85mM 的浓度下，当将毒素施用于宿主和非宿主植物的叶片时，会导致出现坏死斑点。它还会导致浮萍的叶片生长和叶绿素含量减少，并抑制番茄根伸长。最后，在初步的生物测定中，phomentrioloxin 没有显示出任何抗菌、杀菌或杀动物毒性活性。
