Molecular Biology Research Laboratory, Department of Otorhinolaryngology, Charité - Universitätsmedizin Berlin, Campus Charité Mitte Berlin, Germany.
Front Syst Neurosci. 2012 Jun 11;6:47. doi: 10.3389/fnsys.2012.00047. eCollection 2012.
The aim of this review is to focus the attention of clinicians and basic researchers on the association between psycho-social stress and tinnitus. Although tinnitus is an auditory symptom, its onset and progression often associates with emotional strain. Recent epidemiological studies have provided evidence for a direct relationship between the emotional status of subjects and tinnitus. In addition, studies of function, morphology, and gene and protein expression in the auditory system of animals exposed to stress support the notion that the emotional status can influence the auditory system. The data provided by clinical and basic research with use of animal stress models offers valuable clues for an improvement in diagnosis and more effective treatment of tinnitus.
本综述旨在引起临床医生和基础研究人员对心理社会压力与耳鸣之间关系的关注。尽管耳鸣是一种听觉症状，但它的发生和进展常常与情绪紧张有关。最近的流行病学研究为受试者的情绪状态与耳鸣之间的直接关系提供了证据。此外，对暴露于应激的动物的听觉系统的功能、形态以及基因和蛋白质表达的研究支持这样一种观点，即情绪状态可以影响听觉系统。临床和基础研究使用动物应激模型提供的数据为改善耳鸣的诊断和更有效的治疗提供了有价值的线索。
