Borrero I, Fajardo L, Bedoya A, Zea A, Carmona F, de Borrero M F
Department of Microbiology, Universidad del Valle, Cali, Colombia.
Rev Infect Dis. 1990 Nov-Dec;12 Suppl 8:S950-6. doi: 10.1093/clinids/12.supplement_8.s950.
For this study, 340 children less than 18 months old from a low-income, urban neighborhood in Cali, Colombia, were observed from birth by means of weekly home visits to detect cases of acute respiratory tract infection. All suspected cases were confirmed by trained doctors in a special clinic. Information on symptoms, signs, and potential risk factors was documented prospectively. Etiologic agents were identified in cases of lower respiratory tract infection (LRI). The overall incidence of acute respiratory tract infection was 6.6 cases per child-year at risk. The incidence of upper respiratory tract infection was 4.9 cases per child-year at risk and that of LRI was 1.7 cases per child-year at risk. Crowding in the home was found to be significantly associated with an increased incidence of LRI. Respiratory syncytial virus was the viral agent most frequently isolated from cultures of nasopharyngeal aspirates of children with LRI. Staphylococcus aureus was the bacterial agent most frequently isolated from the blood of patients with LRI.
在这项研究中，对来自哥伦比亚卡利市一个低收入城市社区的340名18个月以下儿童从出生起进行观察，通过每周家访来检测急性呼吸道感染病例。所有疑似病例均由经过培训的医生在一家特殊诊所确诊。前瞻性记录了有关症状、体征和潜在风险因素的信息。对下呼吸道感染（LRI）病例确定了病原体。急性呼吸道感染的总体发病率为每儿童年6.6例。上呼吸道感染的发病率为每儿童年4.9例，下呼吸道感染的发病率为每儿童年1.7例。发现家庭拥挤与下呼吸道感染发病率增加显著相关。呼吸道合胞病毒是从下呼吸道感染儿童的鼻咽吸出物培养物中最常分离出的病毒病原体。金黄色葡萄球菌是从下呼吸道感染患者血液中最常分离出的细菌病原体。
