Thorpe Roland J, Ferraro Kenneth F
Res Aging. 2004 Jan 1;26(1):108-129. doi: 10.1177/0164027503258738.
Although there is widespread agreement that obesity (body mass index [BMI] ≥ 30 kg/m(2)) raises health risks, debate has ensued on whether obese older adults are also at greater risk. This study examines the effect of obesity on mortality for younger and older adults to determine whether the risk of obesity is lessened in later life. Data from a 20-year follow-up of a national sample of adults were used to examine the risk of obesity on mortality (N = 6,767). Cox models reveal that obesity raises mortality risk for adults of all ages, but this relationship is nearly twice as strong for persons younger than 50 years of age. Being slightly overweight in later life is associated with lower mortality risk, but obesity raises mortality risk, especially for ischemic heart disease. Obesity in middle age is a grave public health concern, but obesity in later life also merits attention.
尽管人们普遍认为肥胖(体重指数[BMI]≥30kg/m²)会增加健康风险,但对于肥胖的老年人是否也面临更大风险仍存在争议。本研究考察肥胖对年轻人和老年人死亡率的影响,以确定肥胖风险在晚年是否会降低。来自对全国成年人样本进行20年随访的数据被用于考察肥胖对死亡率的风险(N = 6767)。Cox模型显示,肥胖会增加所有年龄段成年人的死亡风险,但这种关系在50岁以下人群中几乎强两倍。晚年稍有超重与较低的死亡风险相关,但肥胖会增加死亡风险,尤其是对于缺血性心脏病。中年肥胖是一个严重的公共卫生问题,但晚年肥胖也值得关注。