Institute of Social and Preventive Medicine, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.
Health Qual Life Outcomes. 2012 Jun 18;10:73. doi: 10.1186/1477-7525-10-73.
Children with mental health problems have been neglected in health-related quality of life (HRQOL) studies. Therefore, the aims of the current study were 1) to assess the influence of the presence of mental or physical health problems on HRQOL; and 2) to analyze the effects of item overlap between mental health problems and HRQOL-measurements.
Proxy- and self-rated HRQOL (KIDSCREEN-27) of children 9-14 years old was assessed across children with mental health problems (n = 535), children with physical health problems (n = 327), and healthy controls (n = 744). Multiple linear regression analyses were conducted with health status, severity of symptoms, status of medication use, gender and nationality as independent, and HRQOL scores as dependent variables. The effects of item overlap were analyzed by repeating regression analyses while excluding those HRQOL items that contextually overlapped the most frequently-occurring mental health problem (attention deficits).
Severity of symptoms was the strongest predictor of reduced HRQOL. However, all other predictors (except for the status of medication use) also contributed to the prediction of some HRQOL scores. Controlling for item overlap did not meaningfully alter the results.
When children with different health constraints are compared, the severity of their particular health problems should be considered. Furthermore, item overlap seems not to be a major problem when the HRQOL of children with mental health problems is studied. Hence, HRQOL assessments are useful to gather information that goes beyond the clinical symptoms of a health problem. This information can, for instance, be used to improve clinical practice.
患有心理健康问题的儿童在健康相关生活质量(HRQOL)研究中被忽视。因此,本研究的目的是 1)评估心理健康或身体健康问题的存在对 HRQOL 的影响;2)分析心理健康问题和 HRQOL 测量之间项目重叠的影响。
评估了 9-14 岁儿童的代理和自我评估 HRQOL(KIDSCREEN-27),这些儿童患有心理健康问题(n=535)、身体健康问题(n=327)和健康对照组(n=744)。使用健康状况、症状严重程度、药物使用状况、性别和国籍作为独立变量,HRQOL 评分作为因变量,进行多元线性回归分析。通过重复回归分析,同时排除最常出现的心理健康问题(注意力缺陷)中上下文重叠最多的 HRQOL 项目,分析项目重叠的影响。
症状严重程度是 HRQOL 降低的最强预测因素。然而,除药物使用状况外的所有其他预测因素(除药物使用状况外)也有助于预测某些 HRQOL 评分。控制项目重叠并没有显著改变结果。
当比较具有不同健康限制的儿童时,应考虑他们特定健康问题的严重程度。此外,当研究心理健康问题儿童的 HRQOL 时,项目重叠似乎不是一个主要问题。因此,HRQOL 评估有助于收集超出健康问题临床症状的信息。这些信息可用于改善临床实践。