• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

人感染禽源甲型 H1N1 流感病毒，中国。

Human infection from avian-like influenza A (H1N1) viruses in pigs, China.

机构信息

State Key Laboratory of Veterinary Biotechnology–Harbin Veterinary Research Institute, Harbin, People’s Republic of China.

出版信息

Emerg Infect Dis. 2012 Jul;18(7):1144-6. doi: 10.3201/eid1807.120009.

DOI:10.3201/eid1807.120009
PMID:22709385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3376805/
Abstract

In investigating influenza in an immunodeficient child in China, in December 2010, we found that the influenza virus showed high sequence identity to that of swine. Serologic evidence indicated that viral persistence in pigs was the source of infection. Continued surveillance of pigs and systemic analysis of swine influenza isolates are needed.

摘要

在调查 2010 年 12 月中国一名免疫功能低下儿童的流感时，我们发现流感病毒与猪源病毒高度同源。血清学证据表明猪群中病毒的持续存在是感染的来源。需要对猪群进行持续监测，并对猪流感分离株进行系统分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a6b/3376805/b9a1206cb451/12-0009-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a6b/3376805/0eaab195d567/12-0009-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a6b/3376805/b9a1206cb451/12-0009-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a6b/3376805/0eaab195d567/12-0009-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a6b/3376805/b9a1206cb451/12-0009-F2.jpg

相似文献

1
Human infection from avian-like influenza A (H1N1) viruses in pigs, China.人感染禽源甲型 H1N1 流感病毒，中国。
Emerg Infect Dis. 2012 Jul;18(7):1144-6. doi: 10.3201/eid1807.120009.
2
Long-term evolution and transmission dynamics of swine influenza A virus.猪流感 A 病毒的长期进化和传播动力学。
Nature. 2011 May 26;473(7348):519-22. doi: 10.1038/nature10004.
3
Avian-like A (H1N1) swine influenza virus antibodies among swine farm residents and pigs in southern China.中国南方猪场居民和猪群中禽源甲型（H1N1）猪流感病毒抗体情况
Jpn J Infect Dis. 2014;67(3):184-90. doi: 10.7883/yoken.67.184.
4
Animal farm: pig in the middle.动物农场：夹在中间的猪。
Nature. 2009 Jun 18;459(7249):889. doi: 10.1038/459889a.
5
Reassortment of pandemic H1N1/2009 influenza A virus in swine.猪流感病毒（H1N1/2009）的重配。
Science. 2010 Jun 18;328(5985):1529. doi: 10.1126/science.1189132.
6
Transmission of influenza A(H1N1) 2009 pandemic viruses in Australian swine.澳大利亚猪群中甲型 H1N1 流感 2009 大流行病毒的传播。
Influenza Other Respir Viruses. 2012 May;6(3):e42-7. doi: 10.1111/j.1750-2659.2012.00337.x. Epub 2012 Feb 15.
7
Evidence of infection with avian, human, and swine influenza viruses in pigs in Cairo, Egypt.埃及开罗猪感染禽流感、人流感和猪流感病毒的证据。
Arch Virol. 2018 Feb;163(2):359-364. doi: 10.1007/s00705-017-3619-3. Epub 2017 Oct 26.
8
Serologic evidence of human influenza virus infections in swine populations, Cambodia.柬埔寨猪群中人类流感病毒感染的血清学证据。
Influenza Other Respir Viruses. 2013 May;7(3):271-9. doi: 10.1111/j.1750-2659.2012.00382.x. Epub 2012 May 30.
9
Isolation and genetic analysis of human origin H1N1 and H3N2 influenza viruses from pigs in China.中国猪源人源H1N1和H3N2流感病毒的分离与基因分析
Biochem Biophys Res Commun. 2007 Apr 27;356(1):91-6. doi: 10.1016/j.bbrc.2007.02.096. Epub 2007 Feb 27.
10
Patchy pig monitoring may hide flu threat.局部猪监测可能掩盖流感威胁。
Nature. 2009 Jun 18;459(7249):894-5. doi: 10.1038/459894b.

引用本文的文献

1
Evaluation of pandemic potential of the genotype 4 (G4) swine influenza virus using and cultures of the human respiratory tract.利用人类呼吸道的原代和传代培养物评估4型（G4）猪流感病毒的大流行潜力。
J Gen Virol. 2025 Jul;106(7). doi: 10.1099/jgv.0.002133.
2
Intranasal Administration of Cold-Adapted Live-Attenuated Eurasian Avian-like H1N1 Vaccine Candidate Confers Protection Against Different-Lineage H1N1 Viruses in Mice.鼻腔接种冷适应减毒活的欧亚禽源样H1N1候选疫苗可使小鼠对不同谱系的H1N1病毒产生保护作用。
Vaccines (Basel). 2025 May 30;13(6):596. doi: 10.3390/vaccines13060596.
3
Emergence of Eurasian Avian-Like Swine Influenza A (H1N1) virus in a child in Shandong Province, China.

本文引用的文献

1
Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.鉴定 HA 和 PB2 中对 H5N1 禽流感病毒在哺乳动物宿主中传播至关重要的氨基酸。
PLoS Pathog. 2009 Dec;5(12):e1000709. doi: 10.1371/journal.ppat.1000709. Epub 2009 Dec 24.
2
From where did the 2009 'swine-origin' influenza A virus (H1N1) emerge?2009 年“猪源”甲型 H1N1 流感病毒源自何处？
Virol J. 2009 Nov 24;6:207. doi: 10.1186/1743-422X-6-207.
3
Human case of swine influenza A (H1N1), Aragon, Spain, November 2008.
中国山东省一名儿童中出现欧亚类禽源性 H1N1 流感病毒。
BMC Infect Dis. 2024 Jun 1;24(1):550. doi: 10.1186/s12879-024-09441-7.
4
The evolution, pathogenicity and transmissibility of quadruple reassortant H1N2 swine influenza virus in China: A potential threat to public health.中国四重重组 H1N2 猪流感病毒的进化、致病性和传染性：对公共卫生的潜在威胁。
Virol Sin. 2024 Apr;39(2):205-217. doi: 10.1016/j.virs.2024.02.002. Epub 2024 Feb 10.
5
A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene.由于其 PA 基因发生突变，一种欧亚类禽流感 H1N1 猪流感重组病毒变得具有致病性和高度传染性。
Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2203919119. doi: 10.1073/pnas.2203919119. Epub 2022 Aug 15.
6
Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses.免疫逃逸适应性突变使欧亚类禽 H1N1 猪流感病毒发生抗原漂移。
J Virol. 2022 Aug 24;96(16):e0097122. doi: 10.1128/jvi.00971-22. Epub 2022 Aug 2.
7
Determining Existing Human Population Immunity as Part of Assessing Influenza Pandemic Risk.评估流感大流行风险的一部分是确定现有人群的免疫情况。
Emerg Infect Dis. 2022 May;28(5):977-985. doi: 10.3201/eid2805.211965.
8
Prevalence, Genetics and Evolutionary Properties of Eurasian Avian-like H1N1 Swine Influenza Viruses in Liaoning.辽宁省欧亚类禽 H1N1 猪流感病毒的流行情况、遗传学特征及进化特性
Viruses. 2022 Mar 20;14(3):643. doi: 10.3390/v14030643.
9
Epidemiology and Genotypic Diversity of Eurasian Avian-Like H1N1 Swine Influenza Viruses in China.中国欧亚类禽 H1N1 猪流感病毒的流行病学和基因多样性。
Virol Sin. 2021 Feb;36(1):43-51. doi: 10.1007/s12250-020-00257-8. Epub 2020 Jul 7.
10
A Systematic Review Analyzing the Prevalence and Circulation of Influenza Viruses in Swine Population Worldwide.一项分析全球猪群中流感病毒流行率和传播情况的系统评价
Pathogens. 2020 May 8;9(5):355. doi: 10.3390/pathogens9050355.
Euro Surveill. 2009 Feb 19;14(7):19120.
4
Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.PB2蛋白第627位氨基酸为赖氨酸（627K）或谷氨酸（627E）以及第701位氨基酸为天冬酰胺（701N）会增加流感病毒在哺乳动物宿主体内的传播。
PLoS Pathog. 2009 Jan;5(1):e1000252. doi: 10.1371/journal.ppat.1000252. Epub 2009 Jan 2.
5
Cases of swine influenza in humans: a review of the literature.人类感染猪流感病例：文献综述
Clin Infect Dis. 2007 Apr 15;44(8):1084-8. doi: 10.1086/512813. Epub 2007 Mar 6.
6
Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model.鸭H5N1流感病毒在哺乳动物小鼠模型中复制的分子基础
J Virol. 2005 Sep;79(18):12058-64. doi: 10.1128/JVI.79.18.12058-12064.2005.
7
High frequency of resistant viruses harboring different mutations in amantadine-treated children with influenza.在接受金刚烷胺治疗的流感儿童中，携带不同突变的耐药病毒出现频率较高。
J Infect Dis. 2003 Jul 1;188(1):57-61. doi: 10.1086/375799. Epub 2003 Jun 23.
8
Frequency of amantadine-resistant influenza A viruses during two seasons featuring cocirculation of H1N1 and H3N2.在H1N1和H3N2共同流行的两个季节中金刚烷胺耐药甲型流感病毒的频率。
J Clin Microbiol. 2003 May;41(5):2164-5. doi: 10.1128/JCM.41.5.2164-2165.2003.
9
The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo.磷酸奥司他韦治疗后甲型H1N1流感病毒神经氨酸酶活性位点的H274Y突变使病毒在体外和体内均受到严重损害。
Antiviral Res. 2002 Aug;55(2):307-17. doi: 10.1016/s0166-3542(02)00053-0.
10
Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses.香港甲型H5N1流感病毒高致病性的分子基础
Science. 2001 Sep 7;293(5536):1840-2. doi: 10.1126/science.1062882.