产金属β-内酰胺酶 GIM-1 在粘质沙雷氏菌临床分离株中的出现。
Emergence of metallo-β-lactamase GIM-1 in a clinical isolate of Serratia marcescens.
机构信息
Medizinisches Versorgungszentrum Dr. Stein, Division of Microbiology, Mönchengladbach, Germany.
出版信息
Antimicrob Agents Chemother. 2012 Sep;56(9):4945-7. doi: 10.1128/AAC.00405-12. Epub 2012 Jun 18.
Abstract
The metallo-β-lactamase GIM-1 (German imipenemase) has been found so far only in clinical isolates of Pseudomonas aeruginosa from Germany. Here we report the detection of bla(GIM-1) in a clinical strain of Serratia marcescens that was isolated from urine, blood, and wound samples over a period of 20 months. The strain was repeatedly isolated from one patient in two German hospitals and an outpatient department located in the region in which all previously described GIM-1-producing P. aeruginosa strains were identified.
摘要
到目前为止，金属β-内酰胺酶 GIM-1（德国亚胺培南酶）仅在来自德国的铜绿假单胞菌临床分离株中发现。在这里，我们报告了在一株来自尿液、血液和伤口样本的粘质沙雷氏菌临床菌株中检测到 bla(GIM-1)。该菌株在 20 个月的时间内，分别从德国两家医院和该地区的一个门诊部的同一位患者身上反复分离出来。所有先前描述的产 GIM-1 铜绿假单胞菌菌株都是在该地区鉴定出来的。
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