在粘质沙雷氏菌克隆株中获得一种质粒介导的 bla(KPC-2) 基因。
In vivo acquisition of a plasmid-mediated bla(KPC-2) gene among clonal isolates of Serratia marcescens.
机构信息
Department of Microbiology, Medical School, University of Athens, Athens, Greece.
出版信息
J Clin Microbiol. 2010 Jul;48(7):2546-9. doi: 10.1128/JCM.00264-10. Epub 2010 May 12.
Abstract
Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes. In two of these cases, the patients were initially infected by carbapenem-susceptible S. marcescens isolates. Molecular typing and plasmid analysis suggested that all three patients had clonally indistinguishable isolates of S. marcescens that acquired a plasmid-mediated bla(KPC-2) gene during the hospitalization.
摘要
三名入住希腊医院的患者感染了对碳青霉烯类药物敏感性降低的粘质沙雷氏菌分离株，这些分离株携带产碳青霉烯酶肺炎克雷伯菌（KPC）。在这两例患者中，最初感染的是对碳青霉烯类药物敏感的粘质沙雷氏菌分离株。分子分型和质粒分析表明，所有这三例患者的粘质沙雷氏菌分离株均具有克隆不可区分的特征，这些分离株在住院期间获得了一种质粒介导的bla(KPC-2)基因。
相似文献
1
In vivo acquisition of a plasmid-mediated bla(KPC-2) gene among clonal isolates of Serratia marcescens.在粘质沙雷氏菌克隆株中获得一种质粒介导的 bla(KPC-2) 基因。
J Clin Microbiol. 2010 Jul;48(7):2546-9. doi: 10.1128/JCM.00264-10. Epub 2010 May 12.
2
Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital.中国一家医院重症监护病房中分离出携带质粒介导的碳青霉烯水解β-内酰胺酶KPC-2的粘质沙雷氏菌、肺炎克雷伯菌和大肠杆菌菌株。
Antimicrob Agents Chemother. 2008 Jun;52(6):2014-8. doi: 10.1128/AAC.01539-07. Epub 2008 Mar 10.
3
Genomic characterization of two carbapenem-resistant isolates causing bacteremia: Emergence of KPC-2-encoding IncR plasmids.两株引起菌血症的耐碳青霉烯类分离株的基因组特征：携带 KPC-2 基因的 IncR 质粒的出现。
Front Cell Infect Microbiol. 2023 Feb 8;13:1075255. doi: 10.3389/fcimb.2023.1075255. eCollection 2023.
4
Plasmid-mediated quinolone resistance in extended-spectrum-β-lactamase- and AmpC β-lactamase-producing Serratia marcescens in China.质粒介导的喹诺酮耐药在产超广谱β-内酰胺酶和 AmpC 酶的中国粘质沙雷氏菌。
Antimicrob Agents Chemother. 2012 Aug;56(8):4529-31. doi: 10.1128/AAC.00493-12. Epub 2012 Jun 4.
5
acquisition and risk of inter-species spread of -plasmid from to in the lower respiratory tract.- 质粒从 到 在下呼吸道中的获得和种间传播的风险。
J Med Microbiol. 2020 Jan;69(1):82-86. doi: 10.1099/jmm.0.001113.
6
Genetic and biochemical characterization of OXA-405, an OXA-48-type extended-spectrum β-lactamase without significant carbapenemase activity.OXA-405的遗传和生化特性，一种无显著碳青霉烯酶活性的OXA-48型超广谱β-内酰胺酶
Antimicrob Agents Chemother. 2015 Jul;59(7):3823-8. doi: 10.1128/AAC.05058-14. Epub 2015 Apr 13.
7
Spread and evolution of bla-plasmid between Serratia marcescens and Klebsiella pneumoniae.黏质沙雷氏菌和肺炎克雷伯菌bla 质粒的传播与进化。
Int J Antimicrob Agents. 2024 May;63(5):107149. doi: 10.1016/j.ijantimicag.2024.107149. Epub 2024 Mar 19.
8
Within-host transition to GES-55 during a GES-6-producing Serratia marcescens outbreak: Emergence of ceftazidime-avibactam resistance and increased susceptibility to carbapenems.在产头孢他啶-阿维巴坦的粘质沙雷氏菌流行期间，宿主内向 GES-55 的转移：头孢他啶-阿维巴坦耐药的出现和对碳青霉烯类药物的易感性增加。
Int J Antimicrob Agents. 2024 Aug;64(2):107257. doi: 10.1016/j.ijantimicag.2024.107257. Epub 2024 Jun 23.
9
Coproduction of KPC-2 and IMP-10 in Carbapenem-Resistant Serratia marcescens Isolates from an Outbreak in a Brazilian Teaching Hospital.在巴西一家教学医院爆发的耐碳青霉烯类粘质沙雷氏菌分离株中KPC-2和IMP-10的共同产生
J Clin Microbiol. 2015 Jul;53(7):2324-8. doi: 10.1128/JCM.00727-15. Epub 2015 Apr 15.
10
Serratia marcescens harbouring SME-type class A carbapenemases in Canada and the presence of blaSME on a novel genomic island, SmarGI1-1.加拿大携带SME型A类碳青霉烯酶的粘质沙雷氏菌以及新型基因组岛SmarGI1-1上blaSME的存在情况
J Antimicrob Chemother. 2014 Jul;69(7):1825-9. doi: 10.1093/jac/dku040. Epub 2014 Mar 21.
引用本文的文献
1
Antimicrobial Treatment of Invasive Infections: Systematic Review.侵袭性感染的抗菌治疗：系统评价
Antibiotics (Basel). 2023 Feb 9;12(2):367. doi: 10.3390/antibiotics12020367.
2
antibiotic resistance mechanisms of an opportunistic pathogen: a literature review.机会性病原体的抗生素耐药机制：文献综述。
PeerJ. 2023 Jan 5;11:e14399. doi: 10.7717/peerj.14399. eCollection 2023.
3
Characterization of a rare metallo-β-lactamase-producing clinical isolate in Hungary.匈牙利一株产罕见金属β-内酰胺酶临床分离株的特性分析
Heliyon. 2020 Jun 27;6(6):e04231. doi: 10.1016/j.heliyon.2020.e04231. eCollection 2020 Jun.
4
First Italian outbreak of VIM-producing in an adult polyvalent intensive care unit, August-October 2018: A case report and literature review.2018年8月至10月，意大利成人多价重症监护病房首次出现产VIM感染：病例报告及文献综述。
World J Clin Cases. 2019 Nov 6;7(21):3535-3548. doi: 10.12998/wjcc.v7.i21.3535.
5
Illumina short-read and MinION long-read WGS to characterize the molecular epidemiology of an NDM-1 Serratia marcescens outbreak in Romania.Illumina 短读长读和 MinION WGS 用于描述罗马尼亚产 NDM-1 粘质沙雷氏菌爆发的分子流行病学。
J Antimicrob Chemother. 2018 Mar 1;73(3):672-679. doi: 10.1093/jac/dkx456.
6
KPC-PRODUCING Serratia marcescens IN A HOME-CARE PATIENT FROM RECIFE, BRAZIL.来自巴西累西腓一名家庭护理患者的产KPC的粘质沙雷氏菌
Rev Inst Med Trop Sao Paulo. 2015 Jul-Aug;57(4):359-60. doi: 10.1590/S0036-46652015000400016.
7
Treatment of Klebsiella pneumoniae carbapenemase (KPC) infections: a review of published case series and case reports.治疗产碳青霉烯酶肺炎克雷伯菌（KPC）感染：已发表的病例系列和病例报告综述。
Ann Clin Microbiol Antimicrob. 2012 Dec 13;11:32. doi: 10.1186/1476-0711-11-32.
8
Emergence of metallo-β-lactamase GIM-1 in a clinical isolate of Serratia marcescens.产金属β-内酰胺酶 GIM-1 在粘质沙雷氏菌临床分离株中的出现。
Antimicrob Agents Chemother. 2012 Sep;56(9):4945-7. doi: 10.1128/AAC.00405-12. Epub 2012 Jun 18.
9
Comparative evaluation of a prototype chromogenic medium (ChromID CARBA) for detecting carbapenemase-producing Enterobacteriaceae in surveillance rectal swabs.检测直肠拭子中产碳青霉烯酶肠杆菌科的原型显色培养基（ChromID CARBA）的比较评估。
J Clin Microbiol. 2012 Jun;50(6):1841-6. doi: 10.1128/JCM.06848-11. Epub 2012 Mar 29.
10
Serratia infections: from military experiments to current practice.沙雷氏菌感染：从军事实验到当前实践。
Clin Microbiol Rev. 2011 Oct;24(4):755-91. doi: 10.1128/CMR.00017-11.
本文引用的文献
1
Genesis of a KPC-producing Klebsiella pneumoniae after in vivo transfer from an imported Greek strain.产 KPC 肺炎克雷伯菌的体内转移起源于一株从希腊进口的菌株。
Euro Surveill. 2010 Jan 7;15(1):19457. doi: 10.2807/ese.15.01.19457-en.
2
Detection of KPC in Acinetobacter spp. in Puerto Rico.波多黎各不动杆菌属中产 KPC 的检测。
Antimicrob Agents Chemother. 2010 Mar;54(3):1354-7. doi: 10.1128/AAC.00899-09. Epub 2009 Dec 28.
3
Interspecies spread of Klebsiella pneumoniae carbapenemase gene in a single patient.在单个患者中肠杆菌科碳青霉烯酶基因的种间传播。
Clin Infect Dis. 2009 Dec 1;49(11):1736-8. doi: 10.1086/648077.
4
Use of boronic acid disk tests to detect extended- spectrum beta-lactamases in clinical isolates of KPC carbapenemase-possessing enterobacteriaceae.使用硼酸盘试验检测产 KPC 碳青霉烯酶肠杆菌科临床分离株中的超广谱β-内酰胺酶。
J Clin Microbiol. 2009 Nov;47(11):3420-6. doi: 10.1128/JCM.01314-09. Epub 2009 Sep 2.
5
Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece.产KPC-2碳青霉烯酶肺炎克雷伯菌菌株在希腊的克隆传播。
J Antimicrob Chemother. 2009 Aug;64(2):348-52. doi: 10.1093/jac/dkp207. Epub 2009 Jun 13.
6
The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria.产肺炎克雷伯菌碳青霉烯酶细菌的真正威胁。
Lancet Infect Dis. 2009 Apr;9(4):228-36. doi: 10.1016/S1473-3099(09)70054-4.
7
First occurrence of KPC-2-possessing Klebsiella pneumoniae in a Greek hospital and recommendation for detection with boronic acid disc tests.希腊一家医院首次出现携带KPC-2的肺炎克雷伯菌及硼酸纸片试验检测建议。
J Antimicrob Chemother. 2008 Dec;62(6):1257-60. doi: 10.1093/jac/dkn364. Epub 2008 Sep 4.
8
Detection of KPC-2 in a clinical isolate of Proteus mirabilis and first reported description of carbapenemase resistance caused by a KPC beta-lactamase in P. mirabilis.奇异变形杆菌临床分离株中KPC-2的检测及首例关于奇异变形杆菌中KPCβ-内酰胺酶引起碳青霉烯类耐药的报道。
J Clin Microbiol. 2008 Sep;46(9):3080-3. doi: 10.1128/JCM.00979-08. Epub 2008 Jul 16.
9
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.对在法国从同一患者分离出的一株大肠杆菌和一株阴沟肠杆菌中鉴定出的超广谱A类β-内酰胺酶KPC-2的传播潜力的遗传学和结构见解。
Antimicrob Agents Chemother. 2008 Oct;52(10):3725-36. doi: 10.1128/AAC.00163-08. Epub 2008 Jul 14.
10
Detection of the Klebsiella pneumoniae carbapenemase type 2 Carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid.在携带共同质粒的弗氏柠檬酸杆菌和产酸克雷伯菌临床分离株中检测2型肺炎克雷伯菌碳青霉烯酶（一种碳青霉烯水解酶）
J Clin Microbiol. 2008 Jun;46(6):2066-9. doi: 10.1128/JCM.02038-07. Epub 2008 Apr 2.
Zotero 插件