Division of Health Outcomes and Health Behaviors, Department of Oncology, Lombardi Comprehensive Cancer, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007, USA.
Fam Cancer. 2012 Sep;11(3):493-502. doi: 10.1007/s10689-012-9541-7.
Hereditary breast and ovarian cancer risk assessments (CRAs) are underutilized by low-income and racial/ethnic minority women, potentially exacerbating cancer-related disparities observed within these populations. We deployed and evaluated a systems-level intervention designed to identify patients potentially at-risk for hereditary breast/ovarian cancer, refer them for CRAs, and facilitate CRA utilization at an urban community-based breast health care center. Cancer family history forms were completed by patients seen at the center during an 18-month period and reviewed by staff for CRA eligibility against published referral criteria. A patient navigator educated eligible patients about the benefits of CRA, navigating interested patients to this service. CRA-specific patient interest and utilization outcomes are reported. In total, 94.7 % of all patients (n = 2,436) completed forms and 65 patients (2.7 %) met CRA eligibility criteria. Most eligible patients (72.3 %) were interested in CRA. Interested patients had a greater risk for hereditary breast/ovarian cancer (i.e., more affected relatives, greater objective risk scores) than uninterested patients: 57.4 % scheduled a CRA appointment and 51.9 % of scheduled patients utilized CRAs. Patients scheduling a CRA were contacted in less time and required fewer follow-up contacts by the patient navigator, and were more likely to be African American, than those who declined a CRA or were lost to follow-up (all p's ≤ .05). The systems-level intervention successfully identified patients eligible for CRA and linked interested and at-risk patients with CRA resources. More intensive patient navigation addressing the unique barriers encountered within this population may be required to enhance utilization.
遗传性乳腺癌和卵巢癌风险评估(CRA)在低收入和少数族裔女性中未得到充分利用,这可能会加剧这些人群中观察到的癌症相关差异。我们部署并评估了一项系统层面的干预措施,旨在确定可能患有遗传性乳腺癌/卵巢癌的患者,将他们转介进行 CRA,并在城市社区乳腺保健中心促进 CRA 的使用。在 18 个月的时间里,中心的患者填写了癌症家族史表格,并由工作人员根据已发布的转诊标准对 CRA 资格进行审查。一名患者导航员向符合条件的患者介绍 CRA 的益处,并引导有兴趣的患者使用这项服务。报告了 CRA 特定的患者兴趣和利用结果。总共,94.7%的患者(n=2436)完成了表格,65 名患者(2.7%)符合 CRA 资格标准。大多数符合条件的患者(72.3%)对 CRA 感兴趣。有兴趣的患者比没有兴趣的患者患遗传性乳腺癌/卵巢癌的风险更高(即,有更多受影响的亲属,更高的客观风险评分):57.4%预约了 CRA 预约,51.9%预约的患者使用了 CRA。与拒绝 CRA 或失访的患者相比(所有 p 值均≤0.05),预约 CRA 的患者与患者导航员联系的时间更短,所需的后续联系也更少,并且更有可能是非洲裔美国人。该系统层面的干预措施成功地确定了符合 CRA 条件的患者,并将有兴趣和有风险的患者与 CRA 资源联系起来。可能需要更密集的患者导航,以解决该人群中遇到的独特障碍,从而提高利用率。