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碳氢化合物暴露、胰腺炎和胆汁酸。

Hydrocarbon exposure, pancreatitis, and bile acids.

作者信息

Hotz P, Pilliod J, Bourgeois R, Boillat M A

机构信息

Institute of Occupational Health, Lausanne.

出版信息

Br J Ind Med. 1990 Dec;47(12):833-7. doi: 10.1136/oem.47.12.833.

Abstract

The data on hydrocarbon induced pancreatitis are conflicting. This question was therefore studied in a non-selected population exposed to hydrocarbons and in "formerly" exposed workers. Neither the past clinical history nor the pancreatic tests provided any evidence for a causal relation between exposure and pancreatitis. No signs of hydrocarbon induced liver damage were seen either. As a healthy worker effect cannot be totally excluded, however, a case-control study in a group of patients suffering from non-alcohol induced pancreatitis could give useful indications for finally excluding the possibility of pancreatitis being induced by hydrocarbons.

摘要

关于烃类诱发胰腺炎的数据相互矛盾。因此,在未经过筛选的接触烃类人群以及“曾经”接触过烃类的工人中对这个问题进行了研究。既往临床病史和胰腺检查均未提供任何证据表明接触与胰腺炎之间存在因果关系。也未发现烃类诱发肝损伤的迹象。然而,由于不能完全排除健康工人效应,因此,在一组非酒精性胰腺炎患者中进行病例对照研究可能会为最终排除烃类诱发胰腺炎的可能性提供有用线索。

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本文引用的文献

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Pentachlorophenol pancreatitis.
Lancet. 1982 Feb 27;1(8270):517. doi: 10.1016/s0140-6736(82)91493-3.
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Letter: Dimethylformamide: a cause of acute pancreatitis?
Lancet. 1974 Aug 10;2(7876):356. doi: 10.1016/s0140-6736(74)91742-5.
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Occupational health hazards from road construction and sealing work.
Ann Occup Hyg. 1986;30(4):445-54. doi: 10.1093/annhyg/30.4.445.

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