Hasin Y, Eisenberg S, Friedlander J, Lewis B S, Gotsman M S
Am Heart J. 1979 Nov;98(5):555-61. doi: 10.1016/0002-8703(79)90279-5.
An analysis was made of correlative factors which might be related to the angiographically measured extent of coronary artery disease in 140 patients. All patients presented with clinically important chest pain. Thirty-three had a normal coronary arteriogram. The extent of the atheromatous process was measured precisely at angiography by three different techniques. A coronary score, based on the percentage of luminal narrowing, was found to be best suited for the analysis. The most important contributory factors to the severity of atherosclerosis was duration of clinical history, number of previous myocardial infarctions, and male sex, but more specifically elevation of serum cholesterol and diabetes mellitus. Cigarette smoking, obesity, hypertension, a family history of atherosclerosis, and elevated serum triglycerides had a positive influence but this was not statistically significant.
对140例患者中可能与冠状动脉造影测量的冠状动脉疾病范围相关的相关因素进行了分析。所有患者均有具有临床意义的胸痛症状。33例患者冠状动脉造影正常。在血管造影时，采用三种不同技术精确测量动脉粥样硬化病变的范围。基于管腔狭窄百分比的冠状动脉评分被发现最适合进行分析。动脉粥样硬化严重程度的最重要促成因素是临床病史的长短、既往心肌梗死的次数和男性性别，但更具体地说是血清胆固醇升高和糖尿病。吸烟、肥胖、高血压、动脉粥样硬化家族史和血清甘油三酯升高有积极影响，但无统计学意义。
