Department of Pediatrics, Rush University Medical Center, Chicago, IL, United States.
Res Dev Disabil. 2012 Nov-Dec;33(6):1948-56. doi: 10.1016/j.ridd.2012.05.024. Epub 2012 Jun 26.
This study investigates the Third Edition of the Bayley Scales of Infant and Toddler Development (Bayley-III) and: (1) early patterns of neurodevelopmental performance among preterm infants 8-12 months of age; and (2) correlations between known risk factors and neurodevelopmental outcome of preterm infants in this cohort. Mean Language Index (LI; 91±15) and Motor Index (MI; 94±17) were significantly lower than the Cognitive Index (CI; 102±15, p<.01). For the majority (53%) of infants, language development was their weakest domain; for another 39%, motor skills were the weakest area of development. Almost one-quarter (22%) of this cohort had mildly delayed language and motor skills, while 7% had significantly delayed language and motor skills. Regression models revealed severely abnormal head ultrasound significantly predicted MI, LI, and CI. Oxygen dependence at discharge predicted CI, LI, and race/ethnicity predicted LI, MI. Results support the addition of the Language Index to the newly revised Bayley-III Scales. Prediction models of developmental performance confirm known neonatal risk factors and reveal sociodemographic risk factors that call for additional research.
本研究调查了第三版贝利婴幼儿发展量表(Bayley-III):(1)8-12 个月早产儿神经发育表现的早期模式;(2)在该队列中,与早产儿神经发育结果相关的已知风险因素。语言指数(LI;91±15)和运动指数(MI;94±17)显著低于认知指数(CI;102±15,p<.01)。对于大多数(53%)婴儿来说,语言发育是他们最薄弱的领域;对于另外 39%的婴儿来说,运动技能是发育最薄弱的领域。该队列中有近四分之一(22%)的婴儿语言和运动技能轻度延迟,而 7%的婴儿语言和运动技能显著延迟。回归模型显示,严重异常的头部超声显著预测了 MI、LI 和 CI。出院时的氧依赖预测了 CI、LI,而种族/民族预测了 LI、MI。结果支持在新修订的贝利-III 量表中添加语言指数。发育表现的预测模型证实了已知的新生儿风险因素,并揭示了社会人口学风险因素,这需要进一步研究。