Université de Bordeaux, Sommeil, Attention et Neuropsychiatrie, USR 3413, F-33000 Bordeaux, France.
Sleep. 2012 Jul 1;35(7):997-1002. doi: 10.5665/sleep.1968.
To evaluate the effects of acute sleep deprivation and chronic sleep restriction on vigilance, performance, and self-perception of sleepiness.
Habitual night followed by 1 night of total sleep loss (acute sleep deprivation) or 5 consecutive nights of 4 hr of sleep (chronic sleep restriction) and recovery night.
Eighteen healthy middle-aged male participants (age [(± standard deviation] = 49.7 ± 2.6 yr, range 46-55 yr).
Multiple sleep latency test trials, Karolinska Sleepiness Scale scores, simple reaction time test (lapses and 10% fastest reaction times), and nocturnal polysomnography data were recorded.
Objective and subjective sleepiness increased immediately in response to sleep restriction. Sleep latencies after the second and third nights of sleep restriction reached levels equivalent to those observed after acute sleep deprivation, whereas Karolinska Sleepiness Scale scores did not reach these levels. Lapse occurrence increased after the second day of sleep restriction and reached levels equivalent to those observed after acute sleep deprivation. A statistical model revealed that sleepiness and lapses did not progressively worsen across days of sleep restriction. Ten percent fastest reaction times (i.e., optimal alertness) were not affected by acute or chronic sleep deprivation. Recovery to baseline levels of alertness and performance occurred after 8-hr recovery night.
In middle-aged study participants, sleep restriction induced a high increase in sleep propensity but adaptation to chronic sleep restriction occurred beyond day 3 of restriction. This sleepiness attenuation was underestimated by the participants. One recovery night restores daytime sleepiness and cognitive performance deficits induced by acute or chronic sleep deprivation.
Philip P; Sagaspe P; Prague M; Tassi P; Capelli A; Bioulac B; Commenges D; Taillard J. Acute versus chronic partial sleep deprivation in middle-aged people: differential effect on performance and sleepiness. SLEEP 2012;35(7):997-1002.
评估急性睡眠剥夺和慢性睡眠限制对警觉性、表现和自我感知的影响。
习惯性夜间睡眠后进行 1 个晚上的完全睡眠剥夺（急性睡眠剥夺）或 5 个连续晚上的 4 小时睡眠（慢性睡眠限制）和恢复性夜间睡眠。
18 名健康的中年男性参与者（年龄[±标准差]为 49.7±2.6 岁，范围 46-55 岁）。
多次睡眠潜伏期测试试验、卡罗林斯卡睡眠量表评分、简单反应时测试（失误和 10%最快反应时间）和夜间多导睡眠图数据。
睡眠限制后立即出现客观和主观的嗜睡增加。睡眠限制后的第二和第三个晚上的睡眠潜伏期达到了与急性睡眠剥夺观察到的水平相当的水平，而卡罗林斯卡睡眠量表评分没有达到这些水平。睡眠限制后的第二天，失误发生率增加，达到了与急性睡眠剥夺观察到的水平相当的水平。统计模型显示，睡眠限制期间的嗜睡和失误并没有随着天数的增加而逐渐恶化。10%最快反应时间（即最佳警觉性）不受急性或慢性睡眠剥夺的影响。经过 8 小时的恢复性夜间睡眠，警觉性和表现恢复到基线水平。
在中年研究参与者中，睡眠限制引起了睡眠倾向的高增加，但对慢性睡眠限制的适应发生在限制的第 3 天之后。这种嗜睡的减轻被参与者低估了。一个恢复性夜间睡眠可以恢复急性或慢性睡眠剥夺引起的白天嗜睡和认知表现缺陷。
